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Amylin/GLP-1Investigational · Phase 3

Amycretin

GLP-1 and amylin receptor agonist. Once weekly (injectable); once daily (oral).

Amycretin (investigational)·Novo Nordisk

Catalog reviewed Sep 30, 2026. Feed checks and price reviews are dated separately below. How we verify. Not medical advice.

OverviewDosing & warningsClinical trials

What to know about Amycretin

An ingredient can have several brands, formulations, and approved uses. Prices and trial findings belong to the specific product and dose shown.

Mean weight change in the cited trial
−24.3% (-24.3% at 36 wks · Phase 1b/2a (subcutaneous) · 60 mg weekly (Phase 1b/2a))

Phase 1b/2a (subcutaneous) · 60 mg weekly (Phase 1b/2a)

FDA shortage report
In development

Investigational. Not FDA-approved.

Route & frequency
Once weekly (injectable); once daily (oral)

Trial averages are not personal predictions. Weight-loss, A1c, and side-effect figures may come from different trials, doses, or populations; follow each source for its context.

Indications

Investigational uses

Amycretin (investigational)

Obesity; type 2 diabetes (investigational)

Obesity (investigational)Type 2 diabetes (investigational)

An investigational single molecule that agonizes both the GLP-1 and amylin receptors, in development as both a once-weekly injection and a once-daily oral tablet.

Product labeling

Dosing, warnings & contraindications

Choose the named product and route. These are submitted label records, which may differ from current approved prescribing information. The product links above lead to current prescribing information. Indexed text omits tables and images; always read the full source label.

No approved label (investigational)

Amycretin is investigational. See its registered studies below. Search DailyMed.

Source: submitted product labeling via openFDA. A listing does not establish FDA approval and may differ from current approved labeling. Read the current prescribing information and consult a clinician.
Evidence

Clinical trials

1 registered trials indexed. Showing up to 12 records: posted results first, then late-phase trials. Registry counts are not a measure of evidence quality.

  • A Research Study of How a New Medicine Called Amycretin, Given as Tablets, Works in Japanese Men With Obesity
    NCT06049329PHASE1Completed36 enrolled

Source: ClinicalTrials.gov API v2 · as of Oct 3, 2026

All trials on ClinicalTrials.gov
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Questions

Common questions about Amycretin

How much weight can you lose on Amycretin?
In its pivotal trial (Phase 1b/2a (subcutaneous)), Amycretin at 60 mg weekly (Phase 1b/2a) showed a mean body-weight change of -24.3% at 36 wks. This is a trial average; individual results vary. Source
Is Amycretin available yet?
No. Amycretin is investigational (Phase 3) and not FDA-approved, so it cannot be prescribed or bought yet.
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