Can you still get compounded tirzepatide and semaglutide?
Prices checked through Nov 6, 2026 · FDA page read Nov 4, 2026
Yes, as of November 2026: 89 US sellers publish a current price for compounded tirzepatide and 87 for compounded semaglutide, read on their own pages. The FDA declared the tirzepatide shortage resolved in December 2024 and the semaglutide shortage in February 2025, which ended the exemption that let pharmacies make copies in bulk, and it has sent warning letters to compounders since. Compounding is now generally limited to patient-specific prescriptions, and compounded drugs are not FDA-approved. FDA (FDA: concerns with unapproved GLP-1 drugs used for weight loss)
Who still sells it, and from what price
Compounded tirzepatide
89 US sellers publish a current price, lowest ≈ $158 per 30 days at Affinity Direct where the supply is stated.
FDA says the shortage was resolved in December 2024. It lists more than 730 adverse event reports.
FDA-approved tirzepatide starts at $320 per 30 days.
Compounded semaglutide
87 US sellers publish a current price, lowest $99 per 30 days at Strut Health where the supply is stated.
FDA says the shortage was resolved in February 2025. It lists 990 adverse event reports.
FDA-approved semaglutide starts at $149 per 30 days.
What the FDA has said since the shortages ended
Its statement to compounders, Apr 1, 2026 FDA (FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize)
“The drug product is compounded for an individual patient based on receipt of a prescription.”
“The compounder does not compound, regularly or in inordinate amounts, any that are essentially copies of a commercially available drug product.”
“This is unless a prescriber determines and documents the compounded drug product contains a change that produces a significant difference from the commercially available drug product for an identified individual patient.”
The FDA says “it does not intend to take action against a compounder for compounding a drug product that is essentially a copy of a commercially available drug product regularly or in inordinate amounts if the compounder fills four or fewer prescriptions of that compounded drug product during a calendar month.”
“Tirzepatide and semaglutide do not currently appear on the 503B bulks list or on FDA’s drug shortage list.”
- “Patients should obtain a prescription from their doctor and fill the prescription at a state-licensed pharmacy.” FDA (FDA: concerns with unapproved GLP-1 drugs used for weight loss)
- “Specifically, your firm compounded products including TIRZEPATIDE/NIACINAMIDE (4 ML)(17/2 MG/ML), SEMAGLUTIDE/CYANOCOBALAMIN (1 ML)(5/0.5 MG/ML), and TIRZEPATIDE/NIACINAMIDE (2.5 ML)(8/2 MG/ML), which appear to be essentially copies of FDA-approved semaglutide and tirzepatide products.” and “The volume of products you are producing suggests that differences between products you are compounding and the FDA-approved products are pretextual.” From its letter of Sep 18, 2026 to Empower Pharmacy. FDA letter (FDA warning letter to Empower Pharmacy)
- “During the inspection, the investigator noted that drug products you produced failed to meet the conditions of section 503B of the FDCA necessary for drugs produced by an outsourcing facility to qualify for exemptions from certain provisions of the FDCA.” From its letter of Apr 7, 2026 to ProRx LLC. FDA letter (FDA warning letter to ProRx)
- “During the inspection, the investigators noted serious deficiencies in your practices for producing drug products, which put patients at risk.” From its letter of Jan 16, 2026 to Boothwyn Pharmacy, LLC. FDA letter (FDA warning letter to Boothwyn Pharmacy)
Every FDA warning letter naming a GLP-1 · which pharmacy each seller names · what each seller adds
Hims, Hers and Ro
Their weight-loss pages, read Nov 6, 2026, do not use the word compounded: Hims (hims.com) (Hims weight-loss page), Hers (forhers.com) (Hers weight-loss page), Ro (ro.co) (Ro weight-loss page). A page can change, so ask them what is on offer now.
Common questions
Can you still get compounded tirzepatide?
89 US sellers publish a current price for it, from ≈ $158 per 30 days at Affinity Direct where the supply is stated. The FDA declared the tirzepatide shortage resolved in December 2024. A prescriber and a pharmacy decide whether a given prescription fits the limits on compounding.
Can you still get compounded semaglutide?
87 US sellers publish a current price for it, from $99 per 30 days at Strut Health where the supply is stated. The FDA declared the semaglutide shortage resolved in February 2025. A prescriber and a pharmacy decide whether a given prescription fits the limits on compounding.
Is compounded tirzepatide legal?
The FDA declared the shortage resolved in December 2024, which ended the exemption that let pharmacies make copies of the approved drug in bulk. In its statement of April 1, 2026, the conditions include: "The drug product is compounded for an individual patient based on receipt of a prescription", and "The compounder does not compound, regularly or in inordinate amounts, any that are essentially copies of a commercially available drug product." It also says: "Tirzepatide and semaglutide do not currently appear on the 503B bulks list or on FDA’s drug shortage list." Whether one prescription fits those limits is for the prescriber and the pharmacy to decide.
Is compounded semaglutide being discontinued?
No date has been set that we have read. 87 US sellers still publish a price today, and the FDA has been writing to compounders since the shortage ended. A seller can stop at any time, so check its page before you rely on a supply.
Did the FDA ban compounded semaglutide and tirzepatide?
The shortages ended, and with them the exemption for making copies in bulk. Compounding for a patient whose medical need an FDA-approved drug cannot meet remains the stated limit. The FDA has sent warning letters to pharmacies, and in one it wrote: "The volume of products you are producing suggests that differences between products you are compounding and the FDA-approved products are pretextual." It also says: "Patients should obtain a prescription from their doctor and fill the prescription at a state-licensed pharmacy."
Is compounded tirzepatide with B12 still allowed?
Some sellers list it. The FDA's statement of April 1, 2026 says: "FDA may consider a compounded drug product that combines semaglutide API and another API, such as vitamin B12 (cyanocobalamin), to be essentially a copy of a commercially available drug product" when the route is the same and the strengths are within 10%. In its letter of Sep 18, 2026 to Empower Pharmacy, it wrote: "Specifically, your firm compounded products including TIRZEPATIDE/NIACINAMIDE (4 ML)(17/2 MG/ML), SEMAGLUTIDE/CYANOCOBALAMIN (1 ML)(5/0.5 MG/ML), and TIRZEPATIDE/NIACINAMIDE (2.5 ML)(8/2 MG/ML), which appear to be essentially copies of FDA-approved semaglutide and tirzepatide products." Which sellers state an additive is on the additives page.
Can you still get compounded semaglutide from Hims, Hers or Ro?
Hims, Hers, and Ro's weight-loss pages, read Nov 6, 2026, do not use the word compounded and name FDA-approved brands. Ask them what is on offer now, since a page can change. The sellers that publish a compounded price are listed on the price pages here.
How much does the FDA-approved version cost instead?
FDA-approved tirzepatide starts at $320 per 30 days and FDA-approved semaglutide at $149 per 30 days at the starting dose, without insurance, from the makers' own programs and other sellers listed here.