US self-pay prices · ordered by price alone

The cheapest GLP-1 online without insurance

Prices checked through Nov 4, 2026

The answer at a glance

  • Lowest FDA-approved

    Foundayo at Amazon Pharmacy

    $149/30 days

    View

  • Lowest FDA-approved injection

    Wegovy pen at Amazon Pharmacy

    $199/28 days · ≈ $213 per 30 days

    View

  • Lowest compounded semaglutide per 30 days

    Strut Health (compounded oral semaglutide lozenge)

    $99/30 days

    View

  • Lowest compounded tirzepatide per 30 days

    Affinity Direct

    $147.90/28 days · ≈ $158 per 30 days

    View

The lowest FDA-approved GLP-1 we can verify without insurance is Foundayo at Amazon Pharmacy, $149/30 days at its starting dose. Among sellers that state the supply a price buys, compounded semaglutide is $99 per 30 days at Strut Health (compounded oral semaglutide lozenge) and compounded tirzepatide is ≈ $158 per 30 days at Affinity Direct, and compounded medication is not FDA-approved. Each price was read on the seller's own page and is dated below.

FDA-approved

FDA-approved GLP-1s: lowest self-pay prices

Lowest cost per 30 days at the starting dose, where the seller states the supply. The price usually rises with the dose.

  1. 1

    Amazon Pharmacy · Foundayo: $149/30 days

    without insurance, 0.8 mg. At 17.2 mg: $299/30 days. Checked Nov 4, 2026.View offer

  2. 2

    Amazon Pharmacy · Wegovy pill: $149/30 days

    without insurance, 1.5 mg. At 25 mg: $299/30 days. Checked Nov 4, 2026.View offer

  3. 3

    GoodRx · Wegovy pill (oral semaglutide): $149-$299/mo ($149 per 30 days)

    by dose. At 25 mg: $299/mo. Checked Nov 4, 2026.View offer

  4. 4

    LillyDirect (Eli Lilly) · Foundayo (LillyDirect self-pay): from $149/mo ($149 per 30 days)

    self-pay cash, lowest dose. At 17.2 mg: $299/mo. Checked Nov 4, 2026.View offer

  5. 5

    NovoCare (Novo Nordisk) · Ozempic tablets: $149/30 days

    self-pay, 1.5 mg dose. At 9 mg: $299/30 days. Checked Nov 4, 2026.View offer

  6. 6

    NovoCare (Novo Nordisk) · Wegovy pill (oral semaglutide): from $149/mo ($149 per 30 days)

    self-pay cash, lowest dose (1.5 mg). At 25 mg: $299/mo. Checked Nov 4, 2026.View offer

FDA-approved

FDA-approved injections: lowest self-pay prices

The same rule, injections only.

  1. 1

    Amazon Pharmacy · Wegovy pen: $199/28 days (≈ $213 per 30 days)

    without insurance, 0.25 mg. At 2.4 mg: $349/28 days. Checked Nov 4, 2026.View offer

  2. 2

    NovoCare (Novo Nordisk) · Ozempic pen: $199/fill initially (≈ $213 per 30 days)

    first two 28-day fills at 0.25 or 0.5 mg for new patients whose prescription is written and received by Dec 31, 2026. At 2 mg: $499/28 days. Checked Nov 4, 2026.View offer

  3. 3

    NovoCare (Novo Nordisk) · Wegovy pen (standard doses 0.25-2.4 mg): $199/fill initially (≈ $213 per 30 days)

    first two 28-day fills at 0.25 or 0.5 mg for new patients whose prescription is written and received by Dec 31, 2026. At 2.4 mg: $349/28 days. Checked Nov 4, 2026.View offer

Compounded · not FDA-approved

Compounded semaglutide: lowest per 30 days

Not FDA-approved. Sellers that state the supply the price buys.

  1. 1

    Strut Health · Compounded oral semaglutide lozenge: $99/30 days

    daily buccal lozenge on the auto-refill plan, 30-day supply. Checked Nov 4, 2026.View offer

  2. 2

    Affinity Direct: $143.65/28 days (≈ $154 per 30 days)

    1-month supply at 0.25 mg weekly on auto-refill every 4 weeks, pause or cancel anytime with no fee. Checked Nov 4, 2026.View offer

  3. 3

    NiceRx: $149/28 days (≈ $160 per 30 days)

    monthly plan billed every 4 weeks. Checked Nov 4, 2026.View offer

Compounded · not FDA-approved

Compounded tirzepatide: lowest per 30 days

Not FDA-approved. Sellers that state the supply the price buys.

  1. 1

    Affinity Direct: $147.90/28 days (≈ $158 per 30 days)

    1-month supply at 2.5 mg weekly on auto-refill every 4 weeks, pause or cancel anytime with no fee. Checked Nov 4, 2026.View offer

  2. 2

    Healthy Living Clinic: $149/4 weeks (≈ $160 per 30 days)

    at 3 to 9 mg a week, paid every 4 weeks. Checked Nov 1, 2026.View offer

  3. 3

    Fifty 410: $199/4 weeks (≈ $213 per 30 days)

    4-week program, $199 total, available in all 50 states. Checked Nov 4, 2026.View offer

Compounded · not FDA-approved

Compounded semaglutide: lowest month to month

Not FDA-approved. Plans that renew each month, by the price the seller advertises.

  1. 1

    Wellmedr: from $41/mo

    monthly plan shipped every 4 weeks, advertised under a "Pre-Black Friday Sale" with no end date. Checked Nov 4, 2026.View offer

  2. 2

    Sunlight: $78/mo

    fall promotion, flat monthly rate locked in at enrollment, month to month. Checked Nov 4, 2026.View offer

  3. 3

    yourEra: $89/mo

    month to month, cancel anytime. Checked Nov 4, 2026.View offer

Compounded · not FDA-approved

Compounded tirzepatide: lowest month to month

Not FDA-approved. Plans that renew each month, by the price the seller advertises.

  1. 1

    Wellmedr: from $71/mo

    monthly plan shipped every 4 weeks, advertised under a "Pre-Black Friday Sale" with no end date. Checked Nov 4, 2026.View offer

  2. 2

    Eden: $129/mo

    one price at every dose. Checked Nov 4, 2026.View offer

  3. 3

    yourEra: $129/mo

    month to month, cancel anytime. Checked Nov 4, 2026.View offer

Pay less

Other ways to lower the price

  • A sale or a first-order code

    16 sellers state one on their own pages today. Most lower the first month only, so read what the next month costs.

    GLP-1 deals and promo codes

  • HSA or FSA money

    Many sellers state that HSA or FSA money can be used, which pays with money you have not paid income tax on.

    What sellers say about HSA and FSA

  • If you have Medicare

    The Medicare GLP-1 Bridge can bring an FDA-approved GLP-1 to $50 a month for those who qualify.

    Who qualifies for the Bridge

  • If you just lost coverage

    What each medication costs without insurance, and the lowest way to stay on the same one.

    Lost GLP-1 coverage

Compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed.

GLPcompare links out only to sellers with a referral program: if you sign up or buy through one of those links, we may earn a commission at no extra cost to you. For other sellers we show the price and the seller's address, and suggest sellers we can link to. It never changes the price you pay or the underlying data. Partner status and commission rates contribute to offer and provider value scores and can change their order. Every partner is labeled. Value scores are not medical recommendations; a higher-ranked offer is not necessarily the lowest price or the right product for you. These lists are in price order, whoever pays.

Questions

Common questions

What is the cheapest GLP-1 without insurance?

The lowest FDA-approved GLP-1 we can verify without insurance is Foundayo at Amazon Pharmacy, $149/30 days at its starting dose. Among sellers that state the supply a price buys, compounded semaglutide is $99 per 30 days at Strut Health (compounded oral semaglutide lozenge) and compounded tirzepatide is ≈ $158 per 30 days at Affinity Direct, and compounded medication is not FDA-approved. Each price was read on the seller's own page and is dated below.

What is the cheapest FDA-approved GLP-1 without insurance?

Foundayo at Amazon Pharmacy, $149/30 days, about $149 per 30 days, checked Nov 4, 2026. The lowest FDA-approved injection is Wegovy pen at Amazon Pharmacy, $199/28 days.

Is a cheap compounded GLP-1 the same as the brand?

No. Compounded medication is not FDA-approved, and the FDA does not review it for safety, effectiveness or quality before it is marketed. A clinician can say which is right for you.

GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.