Compare GLP-1 medications.
US cash prices, trial results and FDA shortage reports. Every figure links to its source.
Search by medication, provider or treatment goal. Examples follow.
15 GLP-1 medications, shortage reports and sourced cash prices
6 approved ingredients
Trial-dose prices · Lowest 30-day cost
Select 2 or 3 ingredients. Results come from separate trials. Compare specific brands.
| Medication | Cash price at trial dose | Trial weight loss | FDA shortage status |
|---|---|---|---|
| At trial dose$299/mo (Self-Pay Journey price for 14.5 mg and 17.2 mg with a refill within 45 days; regular price $349. Eligibility, additional taxes and fees may apply.) 17.2 mg · Foundayo (LillyDirect self-pay) LillyDirect (Eli Lilly) $299 per 30 days at this quoted rate Checked Price conditionsSelf-Pay Journey price for 14.5 mg and 17.2 mg with a refill within 45 days; regular price $349. Eligibility, additional taxes and fees may apply. | Trial weight loss−11.2% (-11.2% at 72 wks · ATTAIN-1 · 17.2 mg daily (Foundayo; 36 mg capsule-equivalent in ATTAIN-1)) ATTAIN-1 · 72 wks 17.2 mg daily (Foundayo; 36 mg capsule-equivalent in ATTAIN-1) 53 ingredient studiesCount checked | FDA statusNo shortage reported | |
| At trial dose$349/28 days (One price for every standard dose (0.25-2.4 mg).) 2.4 mg · Wegovy pen (standard doses 0.25-2.4 mg) NovoCare (Novo Nordisk) ≈ $373.93 per 30 days at this quoted rate Checked Price conditionsOne price for every standard dose (0.25-2.4 mg). | Trial weight loss−14.9% (-14.9% at 68 wks · STEP 1 · 2.4 mg weekly (Wegovy)) STEP 1 · 68 wks 2.4 mg weekly (Wegovy) 769 ingredient studiesCount checked | FDA statusNo shortage reported | |
| At trial dosefrom $389/28 days (The same starting rate is published for 0.75, 1.5, 3 and 4.5 mg. Taxes and additional fees may apply.) 4.5 mg · Trulicity single-dose pens LillyDirect (Eli Lilly) ≈ $416.79 per 30 days at this quoted rate Checked Price conditionsThe same starting rate is published for 0.75, 1.5, 3 and 4.5 mg. Taxes and additional fees may apply. | Trial weight loss≈−4% (-4.6 kg (~4%) at 36 wks · AWARD-11 · 4.5 mg weekly (Trulicity)) AWARD-11 · 36 wks 4.5 mg weekly (Trulicity) 142 ingredient studiesCount checked | FDA statusNo shortage reported | |
| At trial dose$449/28 days (Self Pay Journey price for 7.5-15 mg with a refill within 45 days; otherwise $499 (7.5 mg) or $699 (10-15 mg). Pen needles cost extra.) 15 mg · Zepbound KwikPen (multi-dose pen) LillyDirect (Eli Lilly) ≈ $481.07 per 30 days at this quoted rate Checked Price conditionsSelf Pay Journey price for 7.5-15 mg with a refill within 45 days; otherwise $499 (7.5 mg) or $699 (10-15 mg). Pen needles cost extra. | Trial weight loss−20.9% (-20.9% at 72 wks · SURMOUNT-1 · 15 mg weekly (Zepbound)) SURMOUNT-1 · 72 wks 15 mg weekly (Zepbound) 296 ingredient studiesCount checked | FDA statusNo shortage reported | |
| At trial doseNo verified price at this dose | Trial weight loss≈−3.6% (-3.7 kg (~3.6%) at 30 wks · DURATION-1 · 2 mg weekly (Bydureon)) DURATION-1 · 30 wks 2 mg weekly (Bydureon) 378 ingredient studiesCount checked | FDA statusNo shortage reported | |
| At trial dose~$372/mo (Five pens hold 90 mg: 30 days at the 3 mg daily dose.) 3 mg · Generic liraglutide 3 mg pens (Saxenda generic), GoodRx coupon GoodRx Supply period unverified; excluded from cost ranking. Checked Price conditionsFive pens hold 90 mg: 30 days at the 3 mg daily dose. | Trial weight loss−8% (-8.0% at 56 wks · SCALE Obesity · 3.0 mg daily (Saxenda)) SCALE Obesity · 56 wks 3.0 mg daily (Saxenda) 514 ingredient studiesCount checked | FDA statusIn shortage |
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How this comparison works
GLPcompare compares by the underlying data (price, shortage status, evidence), and a partner never changes a price or a fact. Partner status and commission rates contribute to offer and provider value scores and can affect their order. Every partner is labeled. A value score is not a medical recommendation or a guarantee of the lowest price. We show a figure only when we have a real source for it; when we do not, we show an honest gap, never an invented number.
Read the methodologyLooking at products marketed as GLP-1 alternatives? Read our supplement evidence and patch review.
Common questions
What is the cheapest FDA-approved GLP-1 without insurance?
It depends on the product and dose. Among the self-pay offers we track, FDA-approved GLP-1s start at about $149 per 30 days at a starting dose; at the dose used in its main trial, orforglipron is the lowest at about $299 per 30 days. Compounded versions can cost less but are not FDA-approved. The board above orders every medication by current, sourced price.
Where does the data come from?
Regulatory and study data come from sources including the FDA, DailyMed, ClinicalTrials.gov, and CMS. Cash prices come from manufacturers and providers; third-party price reports are labeled. Published trial results link to their original studies. Each data type has its own source and update schedule.
Is compounded semaglutide the same as Wegovy?
No. Compounded semaglutide and tirzepatide are prepared by compounding pharmacies and are not FDA-approved products; they are not reviewed by the FDA for safety, effectiveness, or quality. We label the difference clearly and never present a compounded or cash price as an FDA-approved list price.