Microdose semaglutide prices
In November 2026, microdose semaglutide typically costs about $149 a month without insurance: the middle of what 15 US sellers advertise per month or 4-week supply, with half of them between $129 and $179. Each plan is compounded semaglutide at a dose below the maintenance doses on the FDA labels. Advertised prices run from $79/mo for microdose semaglutide at CoreAge Rx (a starting price) to $249/mo for microdose semaglutide tablets at Fridays. 2 state the supply the price buys; the lowest of those is ≈ $138 per 30 days for microdose semaglutide at NiceRx. Every price below shows its seller, terms and check date.
Lowest with a stated supply
≈ $138 per 30 days, ranked among 2 plans that state what the price buys
Advertised price
$129/28 days28-day supply (nicerx.com)
≈ $138.21 per 30 days at this quoted rate
Checked
Microdose semaglutide via NiceRx
NiceRx · Sourced provider quote
monthly plan billed every 4 weeks; $249 every 12 weeks on 3 months, $459 every 24 weeks on 6 months, $799 every 48 weeks on 12 months; 0.25 or 0.5 mg weekly at one price; clinician evaluation, medication and delivery included, no membership fee
Price conditions
monthly plan billed every 4 weeks; $249 every 12 weeks on 3 months, $459 every 24 weeks on 6 months, $799 every 48 weeks on 12 months; 0.25 or 0.5 mg weekly at one price; clinician evaluation, medication and delivery included, no membership fee
Available in most U.S. states; the card is charged only if a clinician prescribes. Compounded; not FDA-approved.
28-day supply
Lowest advertised
No verified supply period, so not ranked per 30 days
Advertised price
from $79/moSupply period unverified; excluded from cost ranking.
Checked
Microdose semaglutide via CoreAge Rx
CoreAge Rx · Sourced provider quote
starting price; no membership fees and no long-term contract
Price conditions
starting price; no membership fees and no long-term contract
The same starting price as CoreAge Rx's regular compounded semaglutide. Compounded; not FDA-approved.
The range
- Microdose semaglutide: 15 sellers, advertised from $79/mo to $249/mo; lowest with a stated supply ≈ $138 per 30 days. Regular compounded semaglutide prices
Every cash quote was checked on or after . Each quote shows its own check date. A quoted plan is not a recommendation of a product or a dose. How we source prices
Microdose plans are compounded, off-label and untested in published trials.
Compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed. FDA: concerns with unapproved GLP-1 drugs used for weight loss
Wegovy's label starts the injection at 0.25 mg once weekly for 4 weeks, then raises the dose every 4 weeks; the maintenance dosage for weight reduction in adults is 1.7 mg or 2.4 mg (recommended) once weekly. Wegovy prescribing information (DailyMed, June 30, 2026)
ClinicalTrials.gov lists 3 registered studies of GLP-1 microdosing, none with posted results (checked Oct 19, 2026): AgelessRx's randomized, placebo-controlled early phase 1 trial of microdosed GLP-1 for health, quality of life and longevity measures, planned for 150 people, enrolling by invitation NCT07092605; a University of Texas Health Science Center at Houston phase 2 trial of semaglutide 0.5 mg weekly after a 2 mg course, against stopping, planned for 30 people with HIV, recruiting NCT07325500; Noom's observational cohort (FLOURISH) comparing microdose and standard-dose compounded semaglutide and tirzepatide over 24 months, not yet recruiting NCT07588984.
All microdose semaglutide plans
Telehealth microdose plans for compounded semaglutide, lowest 30-day cost first where the seller states its supply. Regular compounded plans are on their own price pages.
Search by medication, provider or treatment goal. Examples follow.
15 offers · US self-pay
This order ignores commission. Partner links may earn us a referral fee.
- Advertised price$129/28 days
28-day supply (nicerx.com)
≈ $138.21 per 30 days
Checked
Other plan lengths
- $249 for 3 months
- $459 for 6 months
- $799 for 12 months
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: monthly plan billed every 4 weeks; $249 every 12 weeks on 3 months, $459 every 24 weeks on 6 months, $799 every 48 weeks on 12 months; 0.25 or 0.5 mg weekly at one price; clinician evaluation, medication and delivery included, no membership fee
Available in most U.S. states; the card is charged only if a clinician prescribes. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (nicerx.com) - Advertised price$169/28 days
28-day supply (sipra.com)
≈ $181.07 per 30 days
Checked
Other plan lengths
- $139/mo on 3 months ($417 up front)
- $119/mo on 6 months ($714 up front)
- $89/mo on 12 months ($1,068 up front)
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: monthly plan billed every 4 weeks; $139/mo on 3 months ($417 up front), $119/mo on 6 months ($714) or $89/mo on 12 months ($1,068); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost
Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (sipra.com) - Advertised price$99/mo
4-month upfront payment required (agelessrx.com)
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: 4-month plan billed in full, then $159/mo; monthly and 2-month plans also offered at prices shown during sign-up; pause or cancel anytime
Weekly injection formulated with glycine; HSA and FSA accepted. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (agelessrx.com) - Advertised price$129/mo
Supply period unverified; excluded from cost ranking.
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Other plan lengths
- $119/mo on 3 months ($357 up front)
- $109/mo on 6 months ($654 up front)
- $99/mo on 12 months ($1,188 up front)
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: 1-month plan; $119/mo on 3 months ($357), $109/mo on 6 months ($654), $99/mo on 12 months ($1,188), each billed for the period and shown as a limited-time price; free shipping and clinician access included
A subscription that can be cancelled at any time; fully refunded if you are not eligible. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (bmimd.com) - Advertised pricefrom $79/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: starting price; no membership fees and no long-term contract
The same starting price as CoreAge Rx's regular compounded semaglutide. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (coreagerx.com) - Advertised price$129/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: monthly subscription, 90-day supply option; 0.25 to 0.5 mg weekly; free shipping, no membership fee, cancel anytime
Direct Meds says this program is for longevity and metabolic health support, not for active weight loss. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (directmeds.com) - Advertised price$249/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: monthly price of the daily oral tablet on Fridays' microdosing page
Prescribed only if a clinician finds it appropriate; not available in all 50 states. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (joinfridays.com) - Advertised price$174.99/mo
Calculated: $100 medication + $74.99 ongoing membership/provider fee (ivimhealth.com). Charges billed separately.
Separate billing cycles; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
2-month plan; the medication is $75 a month on 4- or 6-month plans, and the $74.99 monthly program fee applies to each. BMI restrictions apply. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (ivimhealth.com) - Advertised price$248/mo
Calculated: $199 medication + $49 ongoing membership/provider fee (lemonaidhealth.com). Charges billed separately.
Separate billing cycles; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Monthly; the $49 membership is required. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (lemonaidhealth.com) - Advertised price$99.99/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: starting dose 0.25 mg weekly; physician-supervised; compounded and shipped from a licensed U.S. pharmacy
Maximus calls low-dose use an off-label use and says its microdosing protocol is not a weight-loss protocol. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (maximustribe.com) - Advertised price$179/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: after $79 for the first 4 weeks of medication (a 3-week initial subscription), on a 12-week subscription, plus tax; medication and the Noom program included; final pricing depends on program selection
Noom's microdose program offers compounded semaglutide and tirzepatide; its page states this one starting price. New-account pricing since July 27, 2026; not available in all states; HSA and FSA eligible. Noom has registered an observational study of its microdose programs (NCT07588984). Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (noom.com) - Advertised price$149/mo
Supply period unverified; excluded from cost ranking.
Checked
Maintenance priceView offerNo separate dose price verified
Price conditions & source
Advertised price: monthly plan only, charged each month; a steady weekly dose set by the provider; medication, provider review, refill coordination, shipping and clinical support included; lab work, when required, may be billed separately
Raeliva offers it for metabolic support as part of a longevity plan, not for weight loss. Compounded; not FDA-approved.
Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.
Read the advertised-price source (raeliva.com)
Read prices in context. Compare the same product, dose, and payment terms. A prepaid monthly rate is not a monthly payment. Cost order uses current, recently checked quotes with documented supply periods, converted to 30 days. Other prices are unranked references. Dose changes, introductory terms and added fees affect what you pay.
Missing prices are not estimated. A listed maintenance dose is not a dosing recommendation.
The FDA declared the tirzepatide (December 2024) and semaglutide (February 2025) shortages resolved, ending the exemption that let pharmacies mass-produce compounded copies, and the 503A/503B enforcement-discretion grace periods ended in 2025. The FDA is now actively enforcing (warning letters and takedowns, including a September 2026 warning letter to Empower Pharmacy, a large compounder, over products it called essentially copies of approved semaglutide and tirzepatide), and in 2026 proposed permanently excluding semaglutide, tirzepatide, and liraglutide from the 503B bulks list (the public comment period, extended 30 days, closed July 30, 2026; a final decision is pending). Liraglutide is different: it is still on the FDA drug shortage list (brand Victoza and Saxenda in limited supply, generics available, as of October 2026). Compounded GLP-1s are not FDA-approved and are now generally limited to narrow, patient-specific 503A prescriptions, so broad low-cost availability has largely wound down. They also carry safety risks the branded products do not: FDA adverse-event reports, at least one sterility recall (ProRx, October 2025), and counterfeit product found in the US supply chain, so a low price is not a low-risk signal. Prices and availability below may lag these changes; confirm current terms with the provider.
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GLPcompare links out only to sellers with a referral program: if you sign up or buy through one of those links, we may earn a commission at no extra cost to you. For other sellers we show the price and the seller's address, and suggest sellers we can link to. It never changes the price you pay or the underlying data. Partner status and commission rates contribute to offer and provider value scores and can change their order. Every partner is labeled. Value scores are not medical recommendations; a higher-ranked offer is not necessarily the lowest price or the right product for you.
Microdose cost at each seller
Each seller's microdose plan beside its own regular plan of the same ingredient. A saving is stated only when both prices say what they buy.
AgelessRx microdose semaglutide cost
- Microdose semaglutide: $99/mo. 4-month plan billed in full, then $159/mo; monthly and 2-month plans also offered at prices shown during sign-up; pause or cancel anytime. Weekly injection formulated with glycine; HSA and FSA accepted. Checked Nov 4, 2026, source (agelessrx.com) (AgelessRx price source).
bmiMD microdose semaglutide cost
- Microdose semaglutide: $129/mo. 1-month plan; $119/mo on 3 months ($357), $109/mo on 6 months ($654), $99/mo on 12 months ($1,188), each billed for the period and shown as a limited-time price; free shipping and clinician access included. A subscription that can be cancelled at any time; fully refunded if you are not eligible. Checked Nov 4, 2026, source (bmimd.com) (bmiMD price source).Regular compounded semaglutide plan: $159/mo.
CoreAge Rx microdose semaglutide cost
- Microdose semaglutide: from $79/mo. Starting price; no membership fees and no long-term contract. The same starting price as CoreAge Rx's regular compounded semaglutide. Checked Nov 4, 2026, source (coreagerx.com) (CoreAge Rx price source).Regular compounded semaglutide plan: from $79/mo.
Direct Meds microdose semaglutide cost
- Microdose semaglutide: $129/mo. Monthly subscription, 90-day supply option; 0.25 to 0.5 mg weekly; free shipping, no membership fee, cancel anytime. Direct Meds says this program is for longevity and metabolic health support, not for active weight loss. Checked Nov 4, 2026, source (directmeds.com) (Direct Meds price source).Regular compounded semaglutide plan: $297/mo.
Fridays microdose semaglutide cost
- Microdose semaglutide tablets: $249/mo. Monthly price of the daily oral tablet on Fridays' microdosing page. Prescribed only if a clinician finds it appropriate; not available in all 50 states. Checked Nov 4, 2026, source (joinfridays.com) (Fridays price source).
Ivim Health microdose semaglutide cost
- Microdose semaglutide: $174.99/mo. Calculated: $100 medication + $74.99 ongoing membership/provider fee. 2-month plan; the medication is $75 a month on 4- or 6-month plans, and the $74.99 monthly program fee applies to each. BMI restrictions apply. Checked Nov 4, 2026, source (ivimhealth.com) (Ivim Health price source).Regular compounded semaglutide plan: $224.99/mo.
Lemonaid Health microdose semaglutide cost
- Microdose semaglutide: $248/mo. Calculated: $199 medication + $49 ongoing membership/provider fee. Monthly; the $49 membership is required. Checked Nov 4, 2026, source (lemonaidhealth.com) (Lemonaid Health price source).Regular compounded semaglutide plan: $348/mo.
Maximus microdose semaglutide cost
- Microdose semaglutide: $99.99/mo. Starting dose 0.25 mg weekly; physician-supervised; compounded and shipped from a licensed U.S. pharmacy. Maximus calls low-dose use an off-label use and says its microdosing protocol is not a weight-loss protocol. Checked Nov 4, 2026, source (maximustribe.com) (Maximus price source).
NiceRx microdose semaglutide cost
- Microdose semaglutide: $129/28 days (≈ $138 per 30 days). Monthly plan billed every 4 weeks; $249 every 12 weeks on 3 months, $459 every 24 weeks on 6 months, $799 every 48 weeks on 12 months; 0.25 or 0.5 mg weekly at one price; clinician evaluation, medication and delivery included, no membership fee. Available in most U.S. states; the card is charged only if a clinician prescribes. Checked Nov 4, 2026, source (nicerx.com) (NiceRx price source).Regular compounded semaglutide plan: $149/28 days, so the microdose plan is $21 less per 30 days than its regular plan.
Noom microdose semaglutide cost
- Microdose GLP-1Rx: $179/mo. After $79 for the first 4 weeks of medication (a 3-week initial subscription), on a 12-week subscription, plus tax; medication and the Noom program included; final pricing depends on program selection. Noom's microdose program offers compounded semaglutide and tirzepatide; its page states this one starting price. New-account pricing since July 27, 2026; not available in all states; HSA and FSA eligible. Noom has registered an observational study of its microdose programs (NCT07588984). Checked Nov 4, 2026, source (noom.com) (Noom price source).Regular compounded semaglutide plan: $279/28 days.
Raeliva microdose semaglutide cost
- Microdose semaglutide: $149/mo. Monthly plan only, charged each month; a steady weekly dose set by the provider; medication, provider review, refill coordination, shipping and clinical support included; lab work, when required, may be billed separately. Raeliva offers it for metabolic support as part of a longevity plan, not for weight loss. Checked Nov 4, 2026, source (raeliva.com) (Raeliva price source).Regular compounded semaglutide plan: $219/mo.
Row Telehealth microdose semaglutide cost
- Microdose semaglutide: $199/mo. Flat monthly program fee for a fixed low weekly dose with no titration schedule; a one-time visit fee is charged on top, $30 asynchronous or $55 live video. Checked Nov 6, 2026, source (rowtelehealth.com) (Row Telehealth price source).Regular compounded semaglutide plan: $299/mo.
Shed microdose semaglutide cost
- Microdose semaglutide: from $149/mo. Starting price; provider-led plan. Checked Nov 4, 2026, source (tryshed.com) (Shed price source).Regular compounded semaglutide plan: $199/mo.
Sipra microdose semaglutide cost
- Microdose semaglutide: $169/28 days (≈ $181 per 30 days). Monthly plan billed every 4 weeks; $139/mo on 3 months ($417 up front), $119/mo on 6 months ($714) or $89/mo on 12 months ($1,068); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost. Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Checked Nov 4, 2026, source (sipra.com) (Sipra price source).Regular compounded semaglutide plan: $199/28 days, so the microdose plan is $32 less per 30 days than its regular plan.
Tomorrow microdose semaglutide cost
- Microdose semaglutide: $149/mo. Billed monthly; $399 billed every 3 months ($133 a month); no membership; renews until cancelled. Checked Nov 6, 2026, source (trytomorrow.com) (Tomorrow price source).Regular compounded semaglutide plan: $199/mo.
Every microdose semaglutide price
Plans that state what the price buys are ranked per 30 days; the rest are listed alphabetically with their own terms.
Ranked per 30 days
- NiceRx (microdose semaglutide): ≈ $138 per 30 days, advertised as $129/28 days. Other plan lengths: $249 for 3 months, $459 for 6 months or $799 for 12 months. Checked Nov 4, 2026, source (nicerx.com) (NiceRx price source).
- Sipra (microdose semaglutide): ≈ $181 per 30 days, advertised as $169/28 days. Other plan lengths: $139/mo on 3 months ($417 up front), $119/mo on 6 months ($714 up front) or $89/mo on 12 months ($1,068 up front). Checked Nov 4, 2026, source (sipra.com) (Sipra price source).
Not ranked: supply period not verified
- AgelessRx (microdose semaglutide): $99/mo. 4-month plan billed in full, then $159/mo; monthly and 2-month plans also offered at prices shown during sign-up; pause or cancel anytime. Checked Nov 4, 2026, source (agelessrx.com) (AgelessRx price source).
- bmiMD (microdose semaglutide): $129/mo. 1-month plan; $119/mo on 3 months ($357), $109/mo on 6 months ($654), $99/mo on 12 months ($1,188), each billed for the period and shown as a limited-time price; free shipping and clinician access included. Checked Nov 4, 2026, source (bmimd.com) (bmiMD price source).
- CoreAge Rx (microdose semaglutide): from $79/mo. Starting price; no membership fees and no long-term contract. Checked Nov 4, 2026, source (coreagerx.com) (CoreAge Rx price source).
- Direct Meds (microdose semaglutide): $129/mo. Monthly subscription, 90-day supply option; 0.25 to 0.5 mg weekly; free shipping, no membership fee, cancel anytime. Checked Nov 4, 2026, source (directmeds.com) (Direct Meds price source).
- Fridays (microdose semaglutide tablets): $249/mo. Monthly price of the daily oral tablet on Fridays' microdosing page. Checked Nov 4, 2026, source (joinfridays.com) (Fridays price source).
- Ivim Health (microdose semaglutide): $174.99/mo. Calculated: $100 medication + $74.99 ongoing membership/provider fee. Checked Nov 4, 2026, source (ivimhealth.com) (Ivim Health price source).
- Lemonaid Health (microdose semaglutide): $248/mo. Calculated: $199 medication + $49 ongoing membership/provider fee. Checked Nov 4, 2026, source (lemonaidhealth.com) (Lemonaid Health price source).
- Maximus (microdose semaglutide): $99.99/mo. Starting dose 0.25 mg weekly; physician-supervised; compounded and shipped from a licensed U.S. pharmacy. Checked Nov 4, 2026, source (maximustribe.com) (Maximus price source).
- Noom (microdose GLP-1Rx): $179/mo. After $79 for the first 4 weeks of medication (a 3-week initial subscription), on a 12-week subscription, plus tax; medication and the Noom program included; final pricing depends on program selection. Checked Nov 4, 2026, source (noom.com) (Noom price source).
- Raeliva (microdose semaglutide): $149/mo. Monthly plan only, charged each month; a steady weekly dose set by the provider; medication, provider review, refill coordination, shipping and clinical support included; lab work, when required, may be billed separately. Checked Nov 4, 2026, source (raeliva.com) (Raeliva price source).
- Row Telehealth (microdose semaglutide): $199/mo. Flat monthly program fee for a fixed low weekly dose with no titration schedule; a one-time visit fee is charged on top, $30 asynchronous or $55 live video. Checked Nov 6, 2026, source (rowtelehealth.com) (Row Telehealth price source).
- Shed (microdose semaglutide): from $149/mo. Starting price; provider-led plan. Checked Nov 4, 2026, source (tryshed.com) (Shed price source).
- Tomorrow (microdose semaglutide): $149/mo. Billed monthly; $399 billed every 3 months ($133 a month); no membership; renews until cancelled. Checked Nov 6, 2026, source (trytomorrow.com) (Tomorrow price source).
Microdose semaglutide cost: common questions
How much does microdosing semaglutide cost without insurance?
In November 2026, microdose semaglutide typically costs about $149 a month without insurance: the middle of what 15 US sellers advertise per month or 4-week supply, with half of them between $129 and $179. 15 US sellers publish a self-pay price for a microdose semaglutide plan, checked between Nov 4, 2026 and Nov 6, 2026. Advertised prices run from $79/mo for microdose semaglutide at CoreAge Rx (a starting price) to $249/mo for microdose semaglutide tablets at Fridays. Among the 2 that state the supply the price buys, costs run from ≈ $138 per 30 days (microdose semaglutide at NiceRx) to ≈ $181 per 30 days (microdose semaglutide at Sipra). Every plan is compounded, and insurance does not cover compounded GLP-1s; these are the sellers' own advertised prices, and the conditions listed with each apply. Regular compounded semaglutide prices
Where can I get microdose semaglutide online in the US?
15 US sellers publish a price for it, checked between Nov 4, 2026 and Nov 6, 2026. Lowest advertised price first: CoreAge Rx (from $79/mo), AgelessRx ($99/mo), Maximus ($99.99/mo), Direct Meds ($129/mo), bmiMD ($129/mo), NiceRx ($129/28 days), Tomorrow ($149/mo), Shed (from $149/mo), Raeliva ($149/mo), Sipra ($169/28 days), Ivim Health ($174.99/mo), Noom ($179/mo), Row Telehealth ($199/mo), Lemonaid Health ($248/mo) and Fridays ($249/mo). Every plan is compounded and needs a prescriber, who decides the dose. Sellers do not all serve every state, so check with the seller before you order.
What is the cheapest microdose semaglutide?
Ranked per 30 days, the lowest is microdose semaglutide at NiceRx at ≈ $138 per 30 days (advertised as $129/28 days), then microdose semaglutide at Sipra (≈ $181 per 30 days). The lowest advertised figure, $79/mo for microdose semaglutide at CoreAge Rx (a starting price), has no verified supply period, so it is not ranked per 30 days. Microdose plans are compounded and not FDA-approved, so a lower price says nothing about quality.
Does microdosing semaglutide cost less than a regular plan?
Only the same seller's two plans can be compared, and only when both state their supply. 2 plans allow that: NiceRx's microdose semaglutide is $21 less per 30 days than its regular plan; Sipra's microdose semaglutide is $32 less per 30 days than its regular plan. At CoreAge Rx, the microdose plan is advertised at the same price as the regular plan.
Is semaglutide microdosing FDA-approved?
No. Every microdose plan tracked here is compounded, and compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed. Wegovy's label starts the injection at 0.25 mg once weekly for 4 weeks, then raises the dose every 4 weeks; the maintenance dosage for weight reduction in adults is 1.7 mg or 2.4 mg (recommended) once weekly. A microdose is a dose below those maintenance doses, chosen by the prescriber. FDA: concerns with unapproved GLP-1 drugs used for weight loss
Has GLP-1 microdosing been tested in clinical trials?
Not with published results. ClinicalTrials.gov lists 3 registered studies of GLP-1 microdosing, none with posted results (checked Oct 19, 2026): AgelessRx's randomized, placebo-controlled early phase 1 trial of microdosed GLP-1 for health, quality of life and longevity measures, planned for 150 people (NCT07092605, enrolling by invitation); a University of Texas Health Science Center at Houston phase 2 trial of semaglutide 0.5 mg weekly after a 2 mg course, against stopping, planned for 30 people with HIV (NCT07325500, recruiting); Noom's observational cohort (FLOURISH) comparing microdose and standard-dose compounded semaglutide and tirzepatide over 24 months (NCT07588984, not yet recruiting). The weight-loss results on the FDA labels come from trials of the full maintenance doses. ClinicalTrials.gov: NCT07092605