S
US self-pay prices

Sipra GLP-1 prices

Compounding

US telehealth: licensed physicians prescribe compounded semaglutide and tirzepatide as weekly injections, dissolving tablets or microdose plans, at one price per plan length at every dose with the membership included; nothing is charged until a physician approves (compounded is not FDA-approved). Sipra has 4 sourced self-pay GLP-1 offers here. Advertised entry prices: Compounded semaglutide $199/28 days; Compounded tirzepatide $299/28 days. Plan terms, fees and the check date are listed with each quote.

4 offers · US self-pay · 0 maintenance quotes

  • Compounded semaglutide dissolving tablets (SemaMelt) via Sipra

    Semaglutide · Compounded

    Compounded · Not FDA-approved
    Advertised price$289/mo

    Supply period unverified; excluded from cost ranking.

    Checked

    Maintenance price

    No separate dose price verified

    View offer
    Price conditions & source

    Advertised price: 1-month plan; $249/mo on 3 months ($747 up front), $219/mo on 6 months ($1,314) or $199/mo on 12 months ($2,388); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost

    Dissolving tablet. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Free shipping to all 50 states. Compounded; not FDA-approved.

    Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.

    Read the advertised-price source
  • Compounded semaglutide via Sipra

    Semaglutide · Compounded

    Compounded · Not FDA-approved
    Advertised price$199/28 days

    28-day supply

    ≈ $213.21 per 30 days

    Checked

    Maintenance price

    No separate dose price verified

    View offer
    Price conditions & source

    Advertised price: monthly plan billed every 4 weeks; $159/mo on 3 months ($477 up front), $129/mo on 6 months ($774) or $99/mo on 12 months ($1,188); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost

    Weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Free shipping to all 50 states. Compounded; not FDA-approved.

    Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.

    Read the advertised-price source
  • Compounded tirzepatide dissolving tablets (TirzaMelt) via Sipra

    Tirzepatide · Compounded

    Compounded · Not FDA-approved
    Advertised price$309/mo

    Supply period unverified; excluded from cost ranking.

    Checked

    Maintenance price

    No separate dose price verified

    View offer
    Price conditions & source

    Advertised price: 1-month plan; $269/mo on 3 months ($807 up front), $249/mo on 6 months ($1,494) or $239/mo on 12 months ($2,868); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost

    Dissolving tablet. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Free shipping to all 50 states. Compounded; not FDA-approved.

    Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.

    Read the advertised-price source
  • Compounded tirzepatide via Sipra

    Tirzepatide · Compounded

    Compounded · Not FDA-approved
    Advertised price$299/28 days

    28-day supply

    ≈ $320.36 per 30 days

    Checked

    Maintenance price

    No separate dose price verified

    View offer
    Price conditions & source

    Advertised price: monthly plan billed every 4 weeks; $249/mo on 3 months ($747 up front), $219/mo on 6 months ($1,314) or $199/mo on 12 months ($2,388); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost

    Weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Free shipping to all 50 states. Compounded; not FDA-approved.

    Confirm the prescribed dose, supply length, membership or consultation fees, and refill conditions with the provider. A listed offer does not confirm eligibility or stock.

    Read the advertised-price source

Read prices in context. Compare the same product, dose, and payment terms. A prepaid monthly rate is not a monthly payment. Cost order uses current, recently checked quotes with documented supply periods, converted to 30 days. Other prices are unranked references. Dose changes, introductory terms and added fees affect what you pay.

Missing prices are not estimated. A listed maintenance dose is not a dosing recommendation.

The FDA declared the tirzepatide (December 2024) and semaglutide (February 2025) shortages resolved, ending the exemption that let pharmacies mass-produce compounded copies, and the 503A/503B enforcement-discretion grace periods ended in 2025. The FDA is now actively enforcing (warning letters and takedowns, including a September 2026 warning letter to Empower Pharmacy, a large compounder, over products it called essentially copies of approved semaglutide and tirzepatide), and in 2026 proposed permanently excluding semaglutide, tirzepatide, and liraglutide from the 503B bulks list (the public comment period, extended 30 days, closed July 30, 2026; a final decision is pending). Liraglutide is different: it is still on the FDA drug shortage list (brand Victoza and Saxenda in limited supply, generics available, as of September 2026). Compounded GLP-1s are not FDA-approved and are now generally limited to narrow, patient-specific 503A prescriptions, so broad low-cost availability has largely wound down. They also carry safety risks the branded products do not: FDA adverse-event reports, at least one sterility recall (ProRx, October 2025), and counterfeit product found in the US supply chain, so a low price is not a low-risk signal. Prices and availability below may lag these changes; confirm current terms with the provider.

Sipra microdose plans

Low-dose plans Sipra sells apart from its regular plans. They are compounded, not FDA-approved, and priced for a dose below the maintenance doses on the FDA labels.

  • Microdose semaglutide: $169/28 days. Monthly plan billed every 4 weeks; $139/mo on 3 months ($417 up front), $119/mo on 6 months ($714) or $89/mo on 12 months ($1,068); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost. Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Checked Oct 24, 2026, source (Sipra microdose price source).Regular plan: $199/28 days, so the microdose plan is $32 less per 30 days than its regular plan.
  • Microdose tirzepatide: $239/28 days. Monthly plan billed every 4 weeks; $199/mo on 3 months ($597 up front), $179/mo on 6 months ($1,074) or $159/mo on 12 months ($1,908); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost. Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. Checked Oct 24, 2026, source (Sipra microdose price source).Regular plan: $299/28 days, so the microdose plan is $64 less per 30 days than its regular plan.
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Questions

Sipra GLP-1 cost: common questions

How much does semaglutide cost through Sipra?

Compounded semaglutide: $199/28 days (monthly plan billed every 4 weeks; $159/mo on 3 months ($477 up front), $129/mo on 6 months ($774) or $99/mo on 12 months ($1,188); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost). Compounded semaglutide dissolving tablets (SemaMelt): $289/mo (1-month plan; $249/mo on 3 months ($747 up front), $219/mo on 6 months ($1,314) or $199/mo on 12 months ($2,388); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost). Checked Oct 24, 2026; each quote links its source in the table. Compounded semaglutide is not an FDA-approved product.

How much does tirzepatide cost through Sipra?

Compounded tirzepatide: $299/28 days (monthly plan billed every 4 weeks; $249/mo on 3 months ($747 up front), $219/mo on 6 months ($1,314) or $199/mo on 12 months ($2,388); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost). Compounded tirzepatide dissolving tablets (TirzaMelt): $309/mo (1-month plan; $269/mo on 3 months ($807 up front), $249/mo on 6 months ($1,494) or $239/mo on 12 months ($2,868); the same price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost). Checked Oct 24, 2026; each quote links its source in the table. Compounded tirzepatide is not an FDA-approved product.

Does Sipra offer FDA-approved GLP-1 medication or compounded versions?

The Sipra offers tracked here are compounded: Compounded semaglutide; Compounded tirzepatide; Compounded semaglutide dissolving tablets (SemaMelt); Compounded tirzepatide dissolving tablets (TirzaMelt). Compounded GLP-1s are not FDA-approved products and are not reviewed by the FDA for safety, effectiveness, or quality.

When were Sipra prices last checked?

Each quote carries its own check date and links the page it was read from: Oct 24, 2026 for the offers here. A quote not rechecked within 21 days is kept as a dated reference and is no longer stated as a current price.

How much does Sipra's microdose GLP-1 cost?

Sipra's microdose semaglutide: $169/28 days (≈ $181 per 30 days). Monthly plan billed every 4 weeks; $139/mo on 3 months ($417 up front), $119/mo on 6 months ($714) or $89/mo on 12 months ($1,068); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost. Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. By comparison, its regular compounded semaglutide plan is $199/28 days (≈ $213 per 30 days), so the microdose plan is $32 less per 30 days than its regular plan. Checked Oct 24, 2026. Sipra's microdose tirzepatide: $239/28 days (≈ $256 per 30 days). Monthly plan billed every 4 weeks; $199/mo on 3 months ($597 up front), $179/mo on 6 months ($1,074) or $159/mo on 12 months ($1,908); one price at every dose; physician review, medication, follow-up messaging and shipping included, membership included at no extra cost. Low-dose weekly injection compounded with B12. Nothing is charged until a physician approves treatment; plans renew until cancelled online. By comparison, its regular compounded tirzepatide plan is $299/28 days (≈ $320 per 30 days), so the microdose plan is $64 less per 30 days than its regular plan. Checked Oct 24, 2026. Microdose GLP-1 prices at every seller

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GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.