US self-pay prices, checked by Nov 8, 2026

Sesame alternatives

Last updated

For Wegovy injection, Sesame lists $448/mo, and at least 6 sellers charge less, starting with Costco Pharmacy at $199/mo for 2 fills. Each is compared like for like: FDA-approved products with the same product, compounded medication with compounded. A lower price is not a recommendation of a seller, a product or a dose.

FDA-approved

Cheaper than Sesame for Wegovy injection

Sesame: $448/mo (Calculated: $349 medication + $99 ongoing membership/provider fee), checked Nov 8, 2026 on sesamecare.com.

  1. Costco Pharmacy: $199/mo for 2 fills (Costco Member Value Pricing at 0.25 to 0.5 mg: "Limited to 2 fills. Price is $349/mo after 12/31/26."). Checked Nov 7, 2026 on rx.costco.com. Trustpilot 3.1 (2 reviews) · BBB A+View offer
  2. Amazon Pharmacy: $199/28 days, about $213 per 30 days (without insurance, 0.25 mg). Checked Nov 4, 2026 on pharmacy.amazon.com. Trustpilot 1.4 (482 reviews)View offer
  3. NovoCare (Novo Nordisk): $199/fill initially, about $213 per 30 days (first two 28-day fills at 0.25 or 0.5 mg for new patients). Checked Nov 4, 2026 on novocare.com.View offer
  4. Hims & Hers: $238 first month (Calculated: $199 medication + $39 introductory membership/provider fee). Checked Nov 4, 2026 on hims.com. Trustpilot 2.9 (9,725 reviews) · 2 FDA warning lettersView offer
  5. LifeMD: $238 first month (Calculated: $199 medication + $39 introductory membership/provider fee). Checked Nov 4, 2026 on lifemd.com. Trustpilot 3.9 (4,293 reviews) · BBB AView offer
  6. Ro: $238 first month (Calculated: $199 medication + $39 introductory membership/provider fee). Checked Nov 4, 2026 on ro.co. Trustpilot 3.9 (7,617 reviews) · BBB A+View offer
FDA-approved

Cheaper than Sesame for Wegovy pill

Sesame: $248/mo (Calculated: $149 medication + $99 ongoing membership/provider fee), checked Nov 8, 2026 on sesamecare.com.

  1. Amazon Pharmacy: $149/30 days, about $149 per 30 days (without insurance, 1.5 mg). Checked Nov 4, 2026 on pharmacy.amazon.com. Trustpilot 1.4 (482 reviews)View offer
  2. Costco Pharmacy: $149/mo (Costco Member Value Pricing at 1.5 mg: "Price is $199/mo after 12/31/26."). Checked Nov 7, 2026 on rx.costco.com. Trustpilot 3.1 (2 reviews) · BBB A+View offer
  3. GoodRx: $149-$299/mo, about $149 per 30 days (by dose). Checked Nov 4, 2026 on goodrx.com. Trustpilot 3.8 (4,073 reviews) · BBB A+View offer
  4. NovoCare (Novo Nordisk): from $149/mo, about $149 per 30 days (self-pay cash, lowest dose (1.5 mg)). Checked Nov 4, 2026 on novocare.com.View offer
  5. WeightWatchers: $174 first month (Calculated: $149 medication + $25 introductory membership/provider fee). Checked Nov 4, 2026 on weightwatchers.com. Trustpilot 4.1 (5,357 reviews)View offer
  6. Ivim Health: $223.99/mo (Calculated: $149 medication + $74.99 ongoing membership/provider fee). Checked Nov 4, 2026 on ivimhealth.com. Trustpilot 4.9 (40,041 reviews) · BBB A+ · 1 FDA warning letterView offer
FDA-approved

Cheaper than Sesame for Zepbound

Sesame: $398/mo (Calculated: $299 medication + $99 ongoing membership/provider fee), checked Nov 8, 2026 on sesamecare.com.

  1. Amazon Pharmacy: $299/28 days, about $320 per 30 days (without insurance, 2.5 mg). Checked Nov 4, 2026 on pharmacy.amazon.com. Trustpilot 1.4 (482 reviews)View offer
  2. LillyDirect (Eli Lilly): $299/28 days, about $320 per 30 days (self-pay cash, starting dose). Checked Nov 4, 2026 on zepbound.lilly.com.View offer
  3. TrumpRx: $299/28 days, about $320 per 30 days (self-pay starting dose). Checked Nov 4, 2026 on zepbound.lilly.com.View offer
  4. WeightWatchers: $324 first month (Calculated: $299 medication + $25 introductory membership/provider fee). Checked Nov 4, 2026 on weightwatchers.com. Trustpilot 4.1 (5,357 reviews)View offer
  5. Hims & Hers: $338 first month (Calculated: $299 medication + $39 introductory membership/provider fee). Checked Nov 4, 2026 on hims.com. Trustpilot 2.9 (9,725 reviews) · 2 FDA warning lettersView offer
  6. LifeMD: $338 first month (Calculated: $299 medication + $39 introductory membership/provider fee). Checked Nov 4, 2026 on lifemd.com. Trustpilot 3.9 (4,293 reviews) · BBB AView offer
FDA-approved

Cheaper than Sesame for Foundayo

Sesame: $248/mo (Calculated: $149 medication + $99 ongoing membership/provider fee), checked Nov 8, 2026 on sesamecare.com.

  1. Amazon Pharmacy: $149/30 days, about $149 per 30 days (without insurance, 0.8 mg). Checked Nov 4, 2026 on pharmacy.amazon.com. Trustpilot 1.4 (482 reviews)View offer
  2. LillyDirect (Eli Lilly): from $149/mo, about $149 per 30 days (self-pay cash, lowest dose). Checked Nov 4, 2026 on lilly.com.View offer
  3. WeightWatchers: $174 first month (Calculated: $149 medication + $25 introductory membership/provider fee). Checked Nov 4, 2026 on weightwatchers.com. Trustpilot 4.1 (5,357 reviews)View offer
  4. Ivim Health: $223.99/mo (Calculated: $149 medication + $74.99 ongoing membership/provider fee). Checked Nov 4, 2026 on ivimhealth.com. Trustpilot 4.9 (40,041 reviews) · BBB A+ · 1 FDA warning letterView offer
Compounded, not FDA-approved

Compounded versions of the same medications

Sesame sells FDA-approved products here, and these are not the same thing. Compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed.

  • Wellmedr: Compounded semaglutide, from $41/mo. Checked Nov 4, 2026 on wellmedr.com.View offer
  • Embody: Compounded semaglutide, flat rate at $49/month. Checked Nov 4, 2026 on joinem.co.View offer
  • CoreAge Rx: Compounded semaglutide, from $79/mo. Checked Nov 4, 2026 on coreagerx.com.View offer
  • BiltRx: Compounded semaglutide, $81/mo. Checked Nov 7, 2026 on biltrx.com.View offer

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Questions

Sesame alternatives: common questions

What is a cheaper alternative to Sesame?

For Wegovy injection, Costco Pharmacy ($199/mo for 2 fills), Amazon Pharmacy ($199/28 days), NovoCare (Novo Nordisk) ($199/fill initially), against Sesame's $448/mo. For Wegovy pill, Amazon Pharmacy ($149/30 days), Costco Pharmacy ($149/mo), GoodRx ($149-$299/mo), against Sesame's $248/mo. For Zepbound, Amazon Pharmacy ($299/28 days), LillyDirect (Eli Lilly) ($299/28 days), TrumpRx ($299/28 days), against Sesame's $398/mo. For Foundayo, Amazon Pharmacy ($149/30 days), LillyDirect (Eli Lilly) (from $149/mo), WeightWatchers ($174 first month), against Sesame's $248/mo. Prices checked by Nov 8, 2026.

How do I switch from Sesame to another seller?

Cancel any renewal with Sesame first, as its terms state, then complete the new seller's intake; a clinician there decides what to prescribe. Ask for your current dose to be considered, since a new prescriber may restart you lower. Moving between brands, or between FDA-approved and compounded medication, is a change to discuss with a clinician.

GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.