Zepbound price without insurance
Zepbound contains tirzepatide and is made by Eli Lilly. Its lowest current self-pay price is $299/28 days, across 8 sourced offers. Prices below are by form and dose, each with its seller, conditions and check date.
Zepbound injection
Once weekly
Advertised entry price
$299-$449/28 days≈ $320.36 per 30 days at this quoted rate
Checked
Zepbound KwikPen (multi-dose pen)
LillyDirect (Eli Lilly) · Manufacturer direct
self-pay cash, by dose ($299 / $399 / $449)
Price conditions
self-pay cash, by dose ($299 / $399 / $449)
Four weekly doses per pen; pen needles must be purchased separately. $299 at 2.5 mg, $399 at 5 mg, and $449 at higher doses under the Self Pay Journey offer with a refill within 45 days.
28-day supply
Published maintenance dose
$449/28 days≈ $481.07 per 30 days at this quoted rate
Checked
At 15 mg
Zepbound KwikPen (multi-dose pen)
LillyDirect (Eli Lilly) · Manufacturer direct
Published price at 15 mg
Price conditions
Published price at 15 mg
Four weekly doses per pen; pen needles must be purchased separately. $299 at 2.5 mg, $399 at 5 mg, and $449 at higher doses under the Self Pay Journey offer with a refill within 45 days.
Self Pay Journey price for 7.5-15 mg with a refill within 45 days; otherwise $499 (7.5 mg) or $699 (10-15 mg). Pen needles cost extra.
28-day supply
Every cash quote was checked on or after . Each quote shows its own check date. A quoted dose is not a dosing recommendation. How we source prices
All Zepbound offers
Manufacturer, pharmacy and telehealth quotes for Zepbound itself. Compounded tirzepatide is a different, unapproved product and is listed on the main price page.
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Compare every GLP-1 priceWhat Zepbound showed in trials
Each result belongs to its named trial and dose. Trial averages do not predict an individual's result.
Zepbound injection
−20.9% (-20.9% at 72 wks · SURMOUNT-1 · 15 mg weekly (Zepbound))SURMOUNT-1 · -20.9% at 72 wks
15 mg weekly (Zepbound)
Accounts for treatment discontinuation
Approved uses
Eligibility, contraindications and warnings are in the full prescribing information.
Zepbound injection
Weight management in adults with obesity, or overweight with a weight-related condition; moderate to severe obstructive sleep apnea in adults with obesity.
US prescribing information (Zepbound Injection prescribing information)Reviewed Sep 6, 2026
Is Zepbound in shortage?
No matching shortage record was returned in the latest complete FDA check. This status covers tirzepatide as a whole; last complete check Oct 9, 2026. National reporting does not confirm stock at your pharmacy.
All GLP-1 shortage reportsZepbound cost: common questions
How much does Zepbound cost without insurance?
$299-$449/28 days at LillyDirect (Eli Lilly) (≈ $320.36 per 30 days at this quoted rate); $449/28 days at 15 mg. These are self-pay prices from the sellers' own pages, not insurance estimates; the conditions and refill rules listed with each quote apply.
What is Zepbound approved for?
Weight management in adults with obesity, or overweight with a weight-related condition; moderate to severe obstructive sleep apnea in adults with obesity.
Is Zepbound in shortage?
No matching shortage record was returned in the latest complete FDA check. This status covers tirzepatide as a whole; last complete check Oct 9, 2026. Confirm local stock with your pharmacy.