How much does a GLP-1 cost without insurance?
Prices checked through Nov 6, 2026
In November 2026, an FDA-approved GLP-1 without insurance costs from $149 per 30 days (Ozempic pill at its starting dose) to $535 per 30 days (Ozempic injection at its top dose), the lowest self-pay prices that state their supply. Compounded medication, which is not FDA-approved, typically costs about $163 a month for semaglutide and $217 a month for tirzepatide.
Where those prices are
Lowest FDA-approved
Foundayo at Amazon Pharmacy
$149/30 days
Lowest FDA-approved injection
Wegovy pen at Amazon Pharmacy
$199/28 days · ≈ $213 per 30 days
Lowest compounded semaglutide per 30 days
Strut Health (compounded oral semaglutide lozenge)
$99/30 days
Lowest compounded tirzepatide per 30 days
Affinity Direct
$147.90/28 days · ≈ $158 per 30 days
What each medication costs, per 30 days and per year
The lowest self-pay price at each dose among sellers that state the supply. A year is that price carried over 365 days, to the nearest $10; sellers do not quote it.
| Medication | Starting dose | Top dose | A year |
|---|---|---|---|
| Ozempic pillNovoCare (Novo Nordisk) (Ozempic tablets), read Nov 4, 2026 | $149 | $299 | $3,640 at the top dose |
| Wegovy pillAmazon Pharmacy (Wegovy pill) and GoodRx (Wegovy pill (oral semaglutide)), read Nov 4, 2026 | $149 | $299 | $3,640 at the top dose |
| FoundayoAmazon Pharmacy (Foundayo) and LillyDirect (Eli Lilly) (Foundayo (LillyDirect self-pay)), read Nov 4, 2026 | $149 | $299 | $3,640 at the top dose |
| Ozempic injectionNovoCare (Novo Nordisk) (Ozempic pen), read Nov 4, 2026 | $213 | $535 | $6,510 at the top dose |
| Wegovy injectionAmazon Pharmacy (Wegovy pen) and NovoCare (Novo Nordisk) (Wegovy pen (standard doses 0.25-2.4 mg)), read Nov 4, 2026 | $213 | $374 | $4,550 at the top dose |
| ZepboundAmazon Pharmacy (Zepbound KwikPen) and LillyDirect (Eli Lilly) (Zepbound KwikPen (multi-dose pen)), read Nov 4, 2026 | $320 | $481 | $5,850 at the top dose |
| TrulicityLillyDirect (Eli Lilly) (Trulicity single-dose pens), read Nov 4, 2026 | $417 | $417 | $5,070 at the top dose |
| Wegovy HDNovoCare (Novo Nordisk) (Wegovy HD pen (7.2 mg)), read Nov 4, 2026 | $428 | $428 | $5,210 at the top dose |
| MounjaroLillyDirect (Eli Lilly) (Mounjaro single-dose pens), read Nov 4, 2026 | $535 | $535 | $6,510 at the top dose |
What compounded GLP-1s typically cost
The middle of what US sellers advertise per month or 4-week supply at the starting dose.
about $163 a month, or about $1,960 a year
Half of 74 sellers charge between $119 and $209.
about $217 a month, or about $2,600 a year
Half of 76 sellers charge between $157 and $299.
Compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed.
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Common questions
How much does a GLP-1 cost per month without insurance?
In November 2026, an FDA-approved GLP-1 without insurance costs from $149 per 30 days (Ozempic pill at its starting dose) to $535 per 30 days (Ozempic injection at its top dose), the lowest self-pay prices that state their supply. Compounded medication, which is not FDA-approved, typically costs about $163 a month for semaglutide and $217 a month for tirzepatide.
How much does a GLP-1 cost per year without insurance?
At the lowest self-pay prices that state their supply, a year costs about $3,640 for Ozempic pill and about $6,510 for Ozempic injection, carried over 365 days at the top dose. Compounded medication at its typical price is about $1,960 a year for semaglutide and $2,600 a year for tirzepatide.
Which GLP-1 is the cheapest without insurance?
The lowest FDA-approved GLP-1 we can verify without insurance is Foundayo at Amazon Pharmacy, $149/30 days at its starting dose. Among sellers that state the supply a price buys, compounded semaglutide is $99 per 30 days at Strut Health (compounded oral semaglutide lozenge) and compounded tirzepatide is ≈ $158 per 30 days at Affinity Direct, and compounded medication is not FDA-approved. Each price was read on the seller's own page and is dated below.
Why do GLP-1 prices differ so much?
Manufacturers price most FDA-approved GLP-1s by strength, so the top dose costs more than the first. Sellers add membership fees, advertise first-month sales and discount longer plans paid upfront. A compounded product is a different thing from the brand: it is not FDA-approved, and the FDA does not review it for safety, effectiveness or quality before it is marketed.