Compounded semaglutide dosage chart, in units
On a U-100 syringe, units = dose in mg ÷ vial strength in mg/mL × 100. 0.25 mg of semaglutide is 5 units at 5 mg/mL and 25 units at 1 mg/mL, so the strength on your own vial changes the number.
Your dose in units
25 units
0.25 mL on a U-100 insulin syringe, where 100 units are 1 mL.
This is arithmetic, not a dose to take. Your vial's label and your prescriber decide. Have your pharmacy or prescriber confirm the number before you inject.
Why the number matters: what FDA reports
- “In these instances, patients administered five to 20 times more than the intended dose of semaglutide.”
- “these patients were directed to administer 5 units from a vial. However, these patients mistakenly administered 50 units instead.”
- “One provider intended to dose 0.25 milligrams (5 units), but prescribed 25 units instead, leading to a patient receiving five times the intended dose and experiencing severe vomiting.”
- “The agency also encourages patients to talk with their health care provider or compounder about how to measure and administer the intended dose of compounded semaglutide or tirzepatide.”
FDA alert: dosing errors with compounded injectable semaglutide (FDA content current as of Jul 26, 2024) · FDA: concerns with unapproved GLP-1 drugs used for weight loss (current as of Oct 1, 2026). Read Nov 6, 2026.
Compounded semaglutide dose chart
Units on a U-100 syringe, with mL beneath, at the doses in the Wegovy label. The strengths are examples: find the one printed on your vial, or use the calculator above. A 1 mL syringe holds 100 units, so a figure above 100 is more than one holds.
| Weekly dose | 1 mg/mL vial | 2.5 mg/mL vial | 5 mg/mL vial |
|---|---|---|---|
| 0.25 mg | 25 units0.25 mL | 10 units0.1 mL | 5 units0.05 mL |
| 0.5 mg | 50 units0.5 mL | 20 units0.2 mL | 10 units0.1 mL |
| 1 mg | 100 units1 mL | 40 units0.4 mL | 20 units0.2 mL |
| 1.7 mg | 170 units1.7 mL | 68 units0.68 mL | 34 units0.34 mL |
| 2.4 mg | 240 units2.4 mL | 96 units0.96 mL | 48 units0.48 mL |
Doses: Wegovy prescribing information (DailyMed, June 30, 2026). Wegovy's label starts the injection at 0.25 mg once weekly for 4 weeks, then raises the dose every 4 weeks; the maintenance dosage for weight reduction in adults is 1.7 mg or 2.4 mg (recommended) once weekly. Compounded semaglutide is not FDA-approved and has no schedule of its own: follow what your prescriber wrote. “FDA is aware that compounders provide semaglutide in various concentrations.”
What compounded semaglutide costs at these doses
Each seller's own advertised self-pay price, per 30 days, where it states the supply the price buys.
Lowest at the starting dose
- Strut Health
$99 per 30 days, advertised as $99/30 days (struthealth.com), checked Nov 4, 2026
- Affinity Direct
≈ $154 per 30 days, advertised as $143.65/28 days (affinitydirect.com), checked Nov 4, 2026
- NiceRx
≈ $160 per 30 days, advertised as $149/28 days (nicerx.com), checked Nov 4, 2026
- Sprout Health
≈ $160 per 30 days, advertised as $149/28 days (joinsprouthealth.com), checked Nov 4, 2026
- Gimme Care
≈ $171 per 30 days, advertised as $160/28 days (gimme.care), checked Nov 4, 2026
Lowest at the top dose (2.4 mg)
- NiceRx
≈ $160 per 30 days at 2.5 mg, advertised as $149/28 days (nicerx.com), checked Nov 4, 2026
- Sprout Health
≈ $160 per 30 days at 2.4 mg, advertised as $149/28 days (joinsprouthealth.com), checked Nov 4, 2026
- Gimme Care
≈ $171 per 30 days at 2.4 mg, advertised as $160/28 days (gimme.care), checked Nov 4, 2026
- Big Easy Weight Loss
≈ $177 per 30 days at 2.4 mg, advertised as from $495/12 weeks (joinbigeasy.com), checked Nov 4, 2026
- Affinity Direct
≈ $181 per 30 days at 2.4 mg, advertised as $169.15/28 days (affinitydirect.com), checked Nov 4, 2026
Compounded semaglutide dosing: common questions
How do I convert compounded semaglutide from mg to units?
Divide your dose in mg by your vial's strength in mg per mL, then multiply by 100. On a U-100 insulin syringe, 100 units are 1 mL. So 0.25 mg from a 1 mg/mL vial is 25 units. FDA has received reports of errors in exactly this step, so have your prescriber or pharmacy confirm the number.
How many units is 0.25 mg of semaglutide?
It depends on the strength printed on your vial. At 1 mg/mL, 0.25 mg is 25 units (0.25 mL) on a U-100 syringe. At 2.5 mg/mL, 0.25 mg is 10 units (0.1 mL) on a U-100 syringe. At 5 mg/mL, 0.25 mg is 5 units (0.05 mL) on a U-100 syringe. Check your vial's label before you draw, and confirm with your prescriber or pharmacy.
How many units is 0.5 mg of semaglutide?
It depends on the strength printed on your vial. At 1 mg/mL, 0.5 mg is 50 units (0.5 mL) on a U-100 syringe. At 2.5 mg/mL, 0.5 mg is 20 units (0.2 mL) on a U-100 syringe. At 5 mg/mL, 0.5 mg is 10 units (0.1 mL) on a U-100 syringe. Check your vial's label before you draw, and confirm with your prescriber or pharmacy.
How many units is 1 mg of semaglutide?
It depends on the strength printed on your vial. At 1 mg/mL, 1 mg is 100 units (1 mL) on a U-100 syringe. At 2.5 mg/mL, 1 mg is 40 units (0.4 mL) on a U-100 syringe. At 5 mg/mL, 1 mg is 20 units (0.2 mL) on a U-100 syringe. Check your vial's label before you draw, and confirm with your prescriber or pharmacy.
How many units is 1.7 mg of semaglutide?
It depends on the strength printed on your vial. At 1 mg/mL, 1.7 mg is 170 units (1.7 mL) on a U-100 syringe. At 2.5 mg/mL, 1.7 mg is 68 units (0.68 mL) on a U-100 syringe. At 5 mg/mL, 1.7 mg is 34 units (0.34 mL) on a U-100 syringe. Check your vial's label before you draw, and confirm with your prescriber or pharmacy.
How many units is 2.4 mg of semaglutide?
It depends on the strength printed on your vial. At 1 mg/mL, 2.4 mg is 240 units (2.4 mL) on a U-100 syringe. At 2.5 mg/mL, 2.4 mg is 96 units (0.96 mL) on a U-100 syringe. At 5 mg/mL, 2.4 mg is 48 units (0.48 mL) on a U-100 syringe. Check your vial's label before you draw, and confirm with your prescriber or pharmacy.
What dose schedule does compounded semaglutide follow?
Compounded semaglutide is not FDA-approved and has no FDA-approved schedule of its own: follow what your prescriber wrote. The doses on this chart are the ones in the FDA-approved Wegovy label: Wegovy's label starts the injection at 0.25 mg once weekly for 4 weeks, then raises the dose every 4 weeks; the maintenance dosage for weight reduction in adults is 1.7 mg or 2.4 mg (recommended) once weekly. FDA says: "the agency has received adverse event reports that may be related to patients prescribed compounded semaglutide or tirzepatide products in doses beyond what is in the FDA-approved drug label." Wegovy dosing, in the label's words
What happens if I draw the wrong number of units?
FDA reports patients taking far more than intended: "In these instances, patients administered five to 20 times more than the intended dose of semaglutide." and "these patients were directed to administer 5 units from a vial. However, these patients mistakenly administered 50 units instead." If you think you took too much, contact your prescriber or Poison Help at 1-800-222-1222.