How much does tirzepatide cost without insurance?
Prices checked through Nov 6, 2026
FDA-approved tirzepatide without insurance, November 2026: Zepbound from $320 per 30 days at the starting dose and $481 at the top dose and Mounjaro from $535 per 30 days at the starting dose. These are the lowest self-pay prices that state their supply. Compounded tirzepatide, which is not FDA-approved, typically costs about $217 a month, with half of 76 US sellers between $157 and $299.
Where those prices are
Lowest per 30 days, compounded
Affinity Direct
$147.90/28 days · ≈ $158 per 30 days
Lowest month to month, compounded
Wellmedr
from $71/mo · a sale price, so check the next month
Lowest at 15 mg, compounded
Gimme Care
$199/28 days at 15 mg · ≈ $213 per 30 days
Lowest with a strong public record, compounded
Collective
$69/mo + $199/yr membership
Lowest FDA-approved
Zepbound KwikPen at Amazon Pharmacy
$299/28 days · ≈ $320 per 30 days
What each medication costs, per 30 days and per year
The lowest self-pay price at each dose among sellers that state the supply. A year is that price carried over 365 days, to the nearest $10; sellers do not quote it.
What compounded tirzepatide typically costs
The middle of what US sellers advertise per month or 4-week supply at the starting dose.
about $217 a month, or about $2,600 a year
Half of 76 sellers charge between $157 and $299.
Compounded drugs are not FDA-approved: the FDA does not review them for safety, effectiveness or quality before they are marketed.
The lowest price at each dose
What each strength costs where a seller publishes it. A course starts low and is mostly paid at a higher dose.
Mounjaro
- 2.5 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
- 5 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
- 7.5 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
- 10 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
- 12.5 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
- 15 mg: from $499/28 daysLillyDirect (Eli Lilly) · ≈ $535 per 30 days
Zepbound
- 2.5 mg: $299/28 daysAmazon Pharmacy and LillyDirect (Eli Lilly) · ≈ $320 per 30 days
- 5 mg: $399/28 daysLillyDirect (Eli Lilly) · ≈ $428 per 30 days
- 7.5 mg: $449/28 daysLillyDirect (Eli Lilly) · ≈ $481 per 30 days
- 10 mg: $449/28 daysLillyDirect (Eli Lilly) · ≈ $481 per 30 days
- 12.5 mg: $449/28 daysLillyDirect (Eli Lilly) · ≈ $481 per 30 days
- 15 mg: $449/28 daysAmazon Pharmacy and LillyDirect (Eli Lilly) · ≈ $481 per 30 days
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Common questions
How much does tirzepatide cost per month without insurance?
FDA-approved tirzepatide without insurance, November 2026: Zepbound from $320 per 30 days at the starting dose and $481 at the top dose and Mounjaro from $535 per 30 days at the starting dose. These are the lowest self-pay prices that state their supply. Compounded tirzepatide, which is not FDA-approved, typically costs about $217 a month, with half of 76 US sellers between $157 and $299.
How much does tirzepatide cost per year without insurance?
About $5,850 a year for Zepbound at the top dose and about $6,510 for Mounjaro at the top dose, carrying the lowest self-pay price over 365 days. Compounded tirzepatide at its typical price is about $2,600 a year. Sellers do not quote these yearly figures; they are that price carried over a year.
Does tirzepatide cost more at a higher dose?
FDA-approved tirzepatide usually does: the manufacturers price it by strength, as the tables on this page show. Among compounded sellers, 50 state a price at 15 mg that is the same as their starting price, so compare at the dose you expect to reach.
What is the cheapest tirzepatide without insurance?
Compounded tirzepatide, which is not FDA-approved: ≈ $158 per 30 days at Affinity Direct among sellers that state the supply a price buys; from $71/mo at Wellmedr month to month, a sale price; ≈ $213 per 30 days at Gimme Care at the full 15 mg dose. FDA-approved tirzepatide: Zepbound KwikPen at Amazon Pharmacy, $299/28 days at the starting dose. Each price was read on the seller's own page and is dated below.
Is compounded tirzepatide the same as the brand?
No. Compounded tirzepatide is not FDA-approved, and the FDA does not review it for safety, effectiveness or quality before it is marketed. A clinician can say which is right for you.