Exenatide vs Semaglutide
Compare the ingredients, then check the specific brand, formulation, and dose. Approved uses and prices vary by product.
| Compare | Exenatide | Semaglutide |
|---|---|---|
| Brands | ||
| Route & frequency | Subcutaneous injection Twice daily (Byetta); once weekly (Bydureon BCise) |
Direct comparative evidence
No direct comparative trial is included for these ingredients in our reviewed catalog. The separate trial results below do not establish which works better.
What the quoted price covers
Lowest tracked quotes for FDA-approved products, selected separately for each price basis. Entry prices may refer to different brands or formulations. Supply periods, eligibility, refill deadlines, and additional fees can change what you pay.
| Compare | Exenatide | Semaglutide |
|---|---|---|
| Advertised entry price | ~$447 per pen Generic exenatide (Amneal) GoodRx GoodRx coupon, lowest listed price for one 5 mcg pen (60 doses: 30 days at the twice-daily dose) Third-party reported price Supply period unverified; excluded from cost ranking. |
Trial outcomes in context
Each result belongs to its own trial, population, dose, and analysis. Weight loss, HbA1c change, and adverse events may come from different studies even within one ingredient. These are study averages, not predictions of your result.
| Compare | Exenatide | Semaglutide |
|---|---|---|
| Weight change | ≈−3.6% (-3.7 kg (~3.6%) at 30 wks · DURATION-1 · 2 mg weekly (Bydureon)) -3.7 kg (~3.6%) at 30 wks DURATION-12 mg weekly (Bydureon) |
Approved uses & full records
Exenatide
Indications depend on the brand and formulation. Read the product-specific indications and prescribing information in the full record.
378 registered ingredient studies. Count checked . Research activity, not a measure of evidence quality.
Open full recordSemaglutide
Indications depend on the brand and formulation. Read the product-specific indications and prescribing information in the full record.
769 registered ingredient studies. Count checked . Research activity, not a measure of evidence quality.
Open full recordCommon questions
Which costs less: Exenatide or Semaglutide?
Compare the named products and price conditions below. A tracked entry quote can be a different brand or formulation from the product studied in a trial. A trial-dose quote applies only to the named product and dose; neither figure is an estimate of your whole treatment cost or an insurance quote.
Do these trial results tell me which medication is best?
Direct trials compare the treatments, doses, and participants they studied. Results from separate trials differ in population, duration, dose, and analysis, so their percentages do not establish a treatment ranking. Discuss your medical history and the specific product label with a licensed clinician.
Does FDA shortage status mean my pharmacy has stock?
No. FDA shortage records describe national supply reports and covered presentations, not inventory at an individual pharmacy. Unknown status means the data cannot establish a current assessment. Confirm local stock with your pharmacy.
Automated feed checks do not constitute a clinical or editorial review. Sources & methodology