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CompareExenatide vs Liraglutide
Ingredient comparison

Exenatide vs Liraglutide

Compare the ingredients, then check the specific brand, formulation, and dose. Approved uses and prices vary by product.

Every cash quote was checked on or after Sep 26, 2026.Data feeds · Oct 3, 2026 UTC
OverviewDirect evidenceCash pricesTrial resultsChange comparison
Exenatide vs Liraglutide: overview
CompareExenatideLiraglutide
Brands

Exenatide

Byetta (discontinued), Bydureon BCise (discontinued), Generic exenatide

GLP-1

Liraglutide

Victoza, Saxenda

GLP-1

Route & frequency

Exenatide

Subcutaneous injection

Twice daily (Byetta); once weekly (Bydureon BCise)

What was tested together

Direct comparative evidence

No direct comparative trial is included for these ingredients in our reviewed catalog. The separate trial results below do not establish which works better.

Product-specific self-pay

What the quoted price covers

Lowest tracked quotes for FDA-approved products, selected separately for each price basis. Entry prices may refer to different brands or formulations. Supply periods, eligibility, refill deadlines, and additional fees can change what you pay.

Exenatide vs Liraglutide: sourced cash quotes
CompareExenatideLiraglutide
Advertised entry price

Exenatide

~$447 per pen

Generic exenatide (Amneal)

GoodRx

GoodRx coupon, lowest listed price for one 5 mcg pen (60 doses: 30 days at the twice-daily dose)

Third-party reported price

Supply period unverified; excluded from cost ranking.

Separate studies

Trial outcomes in context

Each result belongs to its own trial, population, dose, and analysis. Weight loss, HbA1c change, and adverse events may come from different studies even within one ingredient. These are study averages, not predictions of your result.

Exenatide vs Liraglutide: individual trial outcomes
CompareExenatideLiraglutide
Weight change

Exenatide

≈−3.6% (-3.7 kg (~3.6%) at 30 wks · DURATION-1 · 2 mg weekly (Bydureon))

-3.7 kg (~3.6%) at 30 wks

DURATION-1

2 mg weekly (Bydureon)

Check the product label

Approved uses & full records

Exenatide

Indications depend on the brand and formulation. Read the product-specific indications and prescribing information in the full record.

378 registered ingredient studies. Count checked Oct 3, 2026. Research activity, not a measure of evidence quality.

Open full record

Liraglutide

Indications depend on the brand and formulation. Read the product-specific indications and prescribing information in the full record.

514 registered ingredient studies. Count checked Oct 3, 2026. Research activity, not a measure of evidence quality.

Open full record
Reading the comparison

Common questions

Which costs less: Exenatide or Liraglutide?

Compare the named products and price conditions below. A tracked entry quote can be a different brand or formulation from the product studied in a trial. A trial-dose quote applies only to the named product and dose; neither figure is an estimate of your whole treatment cost or an insurance quote.

Do these trial results tell me which medication is best?

Direct trials compare the treatments, doses, and participants they studied. Results from separate trials differ in population, duration, dose, and analysis, so their percentages do not establish a treatment ranking. Discuss your medical history and the specific product label with a licensed clinician.

Does FDA shortage status mean my pharmacy has stock?

No. FDA shortage records describe national supply reports and covered presentations, not inventory at an individual pharmacy. Unknown status means the data cannot establish a current assessment. Confirm local stock with your pharmacy.

Other comparisons
Semaglutide vs LiraglutideSemaglutide vs ExenatideTirzepatide vs LiraglutideTirzepatide vs ExenatideLiraglutide vs DulaglutideLiraglutide vs Orforglipron

Automated feed checks do not constitute a clinical or editorial review. Sources & methodology

GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.
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The live, fully-cited reference for the GLP-1 ecosystem. Every figure traces to its source. Informational only, not medical advice.

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Fazier

Liraglutide

Subcutaneous injection

Once daily

FDA shortage report

Exenatide

National reporting does not confirm stock at your pharmacy.

Coverage & source records

Liraglutide

In shortage

National reporting does not confirm stock at your pharmacy.

Coverage & source records
Checked Sep 30, 2026
Price conditions

GoodRx coupon, lowest listed price for one 5 mcg pen (60 doses: 30 days at the twice-daily dose)

AstraZeneca discontinued both branded products in 2024 (Byetta and Bydureon BCise), and Byetta's approval was withdrawn in 2025. Only generic exenatide (Amneal) remains; residual branded stock may still appear at the pharmacy.

Liraglutide

~$372/mo

Generic liraglutide 3 mg pens (Saxenda generic), GoodRx coupon

GoodRx

GoodRx coupon, lowest listed price for one carton of five 18 mg/3 mL pens

Third-party reported price

Supply period unverified; excluded from cost ranking.

Checked Sep 30, 2026

Price conditions

GoodRx coupon, lowest listed price for one carton of five 18 mg/3 mL pens

GoodRx lists brand Saxenda separately; this is its generic liraglutide listing (Teva launched the first generic GLP-1 for weight loss in August 2025). Prices vary by pharmacy.

At the named trial dose

Exenatide

No sourced quote tracked for this price basis.

Liraglutide

~$372/mo

Generic liraglutide 3 mg pens (Saxenda generic), GoodRx coupon

At 3 mg

GoodRx

Published price at 3 mg

Third-party reported price

Supply period unverified; excluded from cost ranking.

Checked Sep 30, 2026

Price conditions

Published price at 3 mg

GoodRx lists brand Saxenda separately; this is its generic liraglutide listing (Teva launched the first generic GLP-1 for weight loss in August 2025). Prices vary by pharmacy.

Five pens hold 90 mg: 30 days at the 3 mg daily dose.

Explore product prices

Exenatide

All Exenatide offers

Liraglutide

All Liraglutide offers

USD self-pay, not insurance or pharmacy acquisition cost. A trial dose is not a personal dosing recommendation. Compounded offers are shown separately in the offer browser and are not FDA-approved.

Approximation from kilograms; see trial methods

Study context

The oldest GLP-1; a diabetes trial with a modest weight effect.

Liraglutide

−8% (-8.0% at 56 wks · SCALE Obesity · 3.0 mg daily (Saxenda))

-8.0% at 56 wks

SCALE Obesity

3.0 mg daily (Saxenda)

Analysis not classified; see trial methods

HbA1c change (percentage points)

Exenatide

−1.9 pp (-1.9% at 30 wks · DURATION-1 · HbA1c change in percentage points)

-1.9 percentage points at 30 wks

DURATION-1
Study context

The oldest GLP-1; a diabetes trial with a modest weight effect.

Liraglutide

−1.3 pp (-1.3% at 56 wks · SCALE Diabetes · HbA1c change in percentage points)

-1.3 percentage points at 56 wks

SCALE Diabetes
Adverse events

Exenatide

Stopped treatment for adverse events

3.9% (3.9% discontinued for adverse reactions · Bydureon BCise FDA label (2 mg, type 2 diabetes))

Reported nausea

8.2% (Nausea in the drug arm · Bydureon BCise FDA label (2 mg, type 2 diabetes))

Bydureon BCise FDA label (2 mg, type 2 diabetes)

from the FDA label adverse-reactions table (DURATION-1 does not cleanly report AE discontinuation); a diabetes population

Liraglutide

Stopped treatment for adverse events

9.8% (9.8% vs 4.3% placebo (3.0 mg) · FDA Saxenda label, pooled 3.0 mg obesity trials (SCALE))

Reported nausea

39.3% (Nausea in the drug arm · FDA Saxenda label, pooled 3.0 mg obesity trials (SCALE))

FDA Saxenda label, pooled 3.0 mg obesity trials (SCALE)

from the FDA Saxenda adverse-reactions table (the SCALE Obesity trial paper is paywalled); essentially identical to the trial's own ~9.9% / ~40% figures