Foundayo vs Wegovy pill and injection
Foundayo contains orforglipron. Wegovy contains semaglutide. Compare approved uses, formulations, and self-pay prices.
| Compare | Foundayo | Wegovy |
|---|---|---|
| Active ingredient | OrforglipronSmall-molecule GLP-1 | SemaglutideGLP-1 |
| How it is taken | Tablet Once daily, with or without food | Injection Once weekly Tablet Once daily, on an empty stomach |
| Manufacturer | Eli Lilly | Novo Nordisk |
What was actually compared
No direct trial comparing these exact brands is included in our reviewed catalog. Results from separate trials are not a direct comparison of these products.
Weight-loss results by formulation
Each result belongs to its named trial and dose. Separate trials have different participants and methods; these figures are not a direct comparison.
| Compare | Foundayo | Wegovy |
|---|---|---|
| Injection evidence | No reviewed weight-loss result for this brand and formulation. | −14.9% (-14.9% at 68 wks · STEP 1 · 2.4 mg weekly (Wegovy)) STEP 1 · -14.9% at 68 wks 2.4 mg weekly (Wegovy) Accounts for treatment discontinuation |
| Tablet evidence | −11.2% (-11.2% at 72 wks · ATTAIN-1 · 17.2 mg daily (Foundayo; 36 mg capsule-equivalent in ATTAIN-1)) ATTAIN-1 · -11.2% at 72 wks 17.2 mg daily (Foundayo; 36 mg capsule-equivalent in ATTAIN-1) Accounts for treatment discontinuation | −13.6% (-13.6% at 64 wks · OASIS 4 · 25 mg daily (Wegovy tablet)) OASIS 4 · -13.6% at 64 wks 25 mg daily (Wegovy tablet) Accounts for treatment discontinuation |
Entry price and maintenance price
Self-pay quotes, not insurance estimates. Each figure identifies the product, provider, and dose where published.
| Compare | Foundayo | Wegovy |
|---|---|---|
| Injection prices | No reviewed injection formulation in this brand record. | Advertised entry price $199/fill initially28-day supply (novocare.com) ≈ $213.21 per 30 days at this quoted rate Offer through Checked Wegovy pen (standard doses 0.25-2.4 mg)
first two 28-day fills at 0.25 or 0.5 mg for new patients whose prescription is written and received by Dec 31, 2026 Price conditionsfirst two 28-day fills at 0.25 or 0.5 mg for new patients whose prescription is written and received by Dec 31, 2026 After the introductory offer, standard doses cost $349 per box of four pens, a 28-day supply. Wegovy HD (7.2 mg) is $399. Introductory fills must ship by Jan 31, 2027. Eligibility and restrictions apply. 28-day supply Published maintenance dose $349/28 days28-day supply (novocare.com) ≈ $373.93 per 30 days at this quoted rate Checked At 2.4 mg Wegovy pen (standard doses 0.25-2.4 mg)
Published price at 2.4 mg Price conditionsPublished price at 2.4 mg After the introductory offer, standard doses cost $349 per box of four pens, a 28-day supply. Wegovy HD (7.2 mg) is $399. Introductory fills must ship by Jan 31, 2027. Eligibility and restrictions apply. One price for every standard dose (0.25-2.4 mg). 28-day supply |
| Tablet prices | Advertised entry price from $149/mo30-day supply (lilly.com) $149 per 30 days at this quoted rate Checked Foundayo (LillyDirect self-pay)
self-pay cash, lowest dose; ~$25/mo with commercial coverage through the savings card, which ends Dec 31, 2026 Price conditionsself-pay cash, lowest dose; ~$25/mo with commercial coverage through the savings card, which ends Dec 31, 2026 LillyDirect self-pay ladder, each a 30-day supply: $149 (0.8 mg), $199 (2.5 mg), $299 (5.5 and 9 mg), $299 (14.5 and 17.2 mg with a 45-day refill, else $349); the 2.5 mg and 5.5 mg doses are temporarily $149 and $199 through Dec 31, 2026. 30-day supply Published maintenance dose $299/mo30-day supply (lilly.com) $299 per 30 days at this quoted rate Checked At 17.2 mg Foundayo (LillyDirect self-pay)
Published price at 17.2 mg Price conditionsPublished price at 17.2 mg LillyDirect self-pay ladder, each a 30-day supply: $149 (0.8 mg), $199 (2.5 mg), $299 (5.5 and 9 mg), $299 (14.5 and 17.2 mg with a 45-day refill, else $349); the 2.5 mg and 5.5 mg doses are temporarily $149 and $199 through Dec 31, 2026. Self-Pay Journey price for 14.5 mg and 17.2 mg with a refill within 45 days; regular price $349. Eligibility, additional taxes and fees may apply. 30-day supply | Advertised entry price from $149/mo30-day supply (novocare.com) $149 per 30 days at this quoted rate Checked Wegovy pill (oral semaglutide)
self-pay cash, lowest dose (1.5 mg) Price conditionsself-pay cash, lowest dose (1.5 mg) $149/mo for 1.5 mg; $199 for 4 mg; $299 for 9 mg and 25 mg. 30-day supply Published maintenance dose $299/mo30-day supply (novocare.com) $299 per 30 days at this quoted rate Checked At 25 mg Wegovy pill (oral semaglutide)
Published price at 25 mg Price conditionsPublished price at 25 mg $149/mo for 1.5 mg; $199 for 4 mg; $299 for 9 mg and 25 mg. $149 (1.5 mg), $199 (4 mg), $299 (9 mg and 25 mg). 30-day supply |
How these quotes are selected
For each price basis, we prefer a recently checked manufacturer-direct quote, then a recently checked provider quote for that brand and formulation. Within each group, documented 30-day costs come first, lowest to highest. Quotes without a documented supply period have no cost rank. Older quotes appear as dated references only when no current quote is tracked. Providers may differ between entry and maintenance prices. Missing maintenance prices are never replaced with entry prices. Compounded products, combined brand quotes, and membership-only fees are excluded. Prices at different doses are not equivalent treatment costs; confirm supply length, eligibility, and added fees.
Every cash quote was checked on or after . Each quote shows its own check date. A quoted maintenance dose is not a dosing recommendation. Our methodology
Foundayo vs Wegovy side effects
Rate on the medicine, with the placebo rate in brackets, at the highest dose in each label's table. These come from separate trials, so they are not a head-to-head comparison.
| Side effect | Foundayo 17.2 mg | Wegovy 2.4 mg |
|---|---|---|
| Nausea | 35% (10%) | 44% (16%) |
| Diarrhea | 25% (11%) | 30% (16%) |
| Vomiting | 24% (4%) | 24% (6%) |
| Constipation | 24% (9%) | 24% (11%) |
| Abdominal pain | 14% (7%) | 20% (10%) |
| Indigestion | 13% (4%) | 9% (3%) |
| Fatigue | 9% (4%) | 11% (5%) |
| Headache | 9% (7%) | 14% (10%) |
| Dizziness | not in table | 8% (4%) |
| Burping | 8% (1%) | not in table |
| Reflux | 7% (2%) | 5% (3%) |
| Gas | 6% (2%) | 6% (4%) |
| Bloating | 8% (3%) | 7% (5%) |
| Hair loss | 5% (2%) | 3% (1%) |
Foundayo vs Wegovy pill and injection: timing, generics and coverage
Read from each FDA label, FDA's Orange Book and CMS's Part D files, and updated when they change.
| Brand | Soonest top dose | Half-life | Generic approved? | Patent on the medicine to | On Medicare Part D, 2025 |
|---|---|---|---|---|---|
| Wegovy | 7.2 mg from week 21 | about 1 week | No | Dec 5, 2031 | 108,843 |
| Foundayo | 17.2 mg from day 151 | about 29 to 49 hours | No | Sep 26, 2037 | None listed |
How long each takes · Generics and patents · Who covers what
Approved uses by formulation
Eligibility, contraindications, and warnings are in each product's full prescribing information.
| Compare | Foundayo | Wegovy |
|---|---|---|
| Injection | No reviewed injection label in this brand record. Ingredient record | Weight management in eligible adults and adolescents 12+ with obesity; cardiovascular risk reduction in eligible adults; noncirrhotic MASH with moderate to advanced liver fibrosis in adults (accelerated approval). US prescribing information (Wegovy Injection prescribing information)Reviewed Nov 4, 2026 |
| Tablet | Weight management in adults with obesity, or overweight with a weight-related condition. US prescribing information (Foundayo Tablet prescribing information)Reviewed Nov 4, 2026 | Weight management and cardiovascular risk reduction in eligible adults. The tablet is not labeled for MASH or pediatric use. US prescribing information (Wegovy Tablet prescribing information)Reviewed Nov 4, 2026 |
Full evidence and safety information
What changed for Foundayo and Wegovy
- TrialResults posted for a Semaglutide study: Lifestyle Counseling and Medication for Adolescent Weight Management
- PricebmiMD: Compounded semaglutide via bmiMD now $129/mo (was $159/mo) (read on bmimd.com)
- PriceSunlight: Compounded semaglutide via Sunlight now $78/mo (was $88/mo) (read on sunlight.com)
- PriceWellorithm: Compounded semaglutide via Wellorithm now $299/mo (was $247/mo) (read on wellorithm.com)
- TrialResults posted for a Semaglutide study: Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
- PriceMEDVi: Compounded semaglutide via MEDVi now $199/mo (was $299/mo) (read on glp1.medvi.org)
Written from each source's own record as it changes. Every change on GLPcompare
Foundayo vs Wegovy pill and injection: common questions
Is Foundayo the same as Wegovy?
No. Foundayo contains orforglipron and Wegovy contains semaglutide, which are different medicines.
Is Foundayo or Wegovy better for weight loss?
No trial on our list compared them directly. In separate trials: Foundayo -11.2% at 72 wks in ATTAIN-1 (17.2 mg daily (Foundayo; 36 mg capsule-equivalent in ATTAIN-1)); Wegovy -14.9% at 68 wks in STEP 1 (2.4 mg weekly (Wegovy)). Separate trials enrolled different people for different lengths of time, so these figures cannot rank them.
Is Foundayo or Wegovy safer?
We know of no trial set up to answer that. Stopping because of side effects, each in its own trial and not a head-to-head figure: Foundayo 10.3% vs 2.7% placebo (36 mg) (ATTAIN-1 (36 mg, 72 wks, obesity)); Wegovy 7.0% vs 3.1% placebo (STEP 1 (2.4 mg, 68 wks, obesity)). Each FDA label lists its own warnings, and which ones matter depends on your health. Side effects compared, from each FDA label
What Wegovy dose is equivalent to Foundayo?
No FDA label sets a dose of Foundayo that equals a dose of Wegovy, and we know of no trial that defines one. Switching is a prescriber's decision, and each label sets its own starting dose and steps. Each label's doses and steps