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Indication

GLP-1 medications for Cardiovascular risk reduction

GLP-1 medications for Cardiovascular risk reduction, with sourced prices, shortage reports and study results.

Last checked · Oct 3, 2026 UTC
4approved

Approved for this use

Alphabetical by active ingredient. Approved uses depend on the specific brand and formulation.

GLP-1

Dulaglutide

Trulicity

Subcutaneous injection · Once weekly

FDA shortage report

Published entry quote

from $389/28 days

Trulicity single-dose pens · LillyDirect (Eli Lilly)

Checked Sep 30, 2026

Price conditions

self-pay, four weekly pens; published starting rate at each dose

The self-pay program requires a prescription for an approved use, age 18+, and US or Puerto Rico residence. Purchases cannot be submitted to insurance or counted toward deductibles or out-of-pocket limits. Four once-weekly pens cover 28 days.

28-day supply

Checked Sep 30, 2026. Entry quotes are not estimates of ongoing treatment cost.

Prices, evidence & safety
GLP-1

Liraglutide

Victoza, Saxenda

Subcutaneous injection · Once daily

FDA shortage reportIn shortage

Published entry quote

~$372/mo

Generic liraglutide 3 mg pens (Saxenda generic), GoodRx coupon · GoodRx

Checked Sep 30, 2026

Price conditions
GLP-1

Semaglutide

Ozempic, Wegovy, Wegovy HD, Rybelsus

Subcutaneous injection (Ozempic, Wegovy); oral tablet (Rybelsus, oral Ozempic, Wegovy pill) · Once weekly (injectable); once daily (oral)

FDA shortage report

Published entry quote

$149-$299/mo

Wegovy pill (oral semaglutide) via GoodRx · GoodRx

Checked Sep 30, 2026

Price conditions
GIP/GLP-1

Tirzepatide

Mounjaro, Zepbound

Subcutaneous injection · Once weekly

FDA shortage report

Published entry quote

$299-$449/28 days

Zepbound KwikPen (multi-dose pen) · LillyDirect (Eli Lilly)

Checked Sep 30, 2026

Price conditions
Other indications
Type 2 diabetes12Chronic weight management12MASH3Chronic kidney disease in type 2 diabetes1Obstructive sleep apnea with obesity1All GLP-1 drugs
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Fazier

GoodRx coupon, lowest listed price for one carton of five 18 mg/3 mL pens

GoodRx lists brand Saxenda separately; this is its generic liraglutide listing (Teva launched the first generic GLP-1 for weight loss in August 2025). Prices vary by pharmacy.

Third-party reported price.

Checked Sep 30, 2026. Entry quotes are not estimates of ongoing treatment cost.

Prices, evidence & safety

by dose; Novo Nordisk's self-pay price through a GoodRx coupon

The same oral semaglutide and prices as the NovoCare offer: $149 (1.5 mg), $199 (4 mg), $299 (9 mg and 25 mg), per Novo Nordisk's published self-pay ladder. FDA-approved product.

30-day supply

Third-party reported price.

Checked Sep 30, 2026. Entry quotes are not estimates of ongoing treatment cost.

Prices, evidence & safety

self-pay cash, by dose ($299 / $399 / $449)

Four weekly doses per pen; pen needles must be purchased separately. $299 at 2.5 mg, $399 at 5 mg, and $449 at higher doses under the Self Pay Journey offer with a refill within 45 days.

28-day supply

Checked Sep 30, 2026. Entry quotes are not estimates of ongoing treatment cost.

Prices, evidence & safety
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