From each FDA label

Can you take a GLP-1 while pregnant?

Wegovy, Zepbound, Foundayo and Saxenda say weight loss offers no benefit to a pregnant patient and may cause fetal harm. Ozempic, Rybelsus/Ozempic tablets, Mounjaro, Trulicity and Byetta say the human data are too limited to determine a risk. Tell your prescriber if you are pregnant or plan to be.

Read from each manufacturer's FDA label on DailyMed. The newest revision saying anything on this is Aug 28, 2026.

Word for word

What each label says about pregnancy

Sentences from each label, in its own words. Only cross-references are removed.

Wegovy

  • Weight loss offers no benefit to a pregnant patient and may cause fetal harm.
  • When a pregnancy is recognized, advise the pregnant patient of the risk to a fetus.
  • Discontinue Wegovy in pregnant patients who are using it for weight reduction.
  • Whether Wegovy treatment during pregnancy reduces these risks is unknown.

Label revised Jun 18, 2026. DailyMed

Ozempic

  • There are limited data with semaglutide use in pregnant women to inform a drug-associated risk for adverse developmental outcomes.
  • There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.
  • Based on animal reproduction studies, there may be potential risks to the fetus from exposure to semaglutide during pregnancy.
  • Ozempic should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Label revised Jun 1, 2026. DailyMed

Rybelsus and Ozempic tablets

  • Available data with semaglutide use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal outcomes.
  • There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.
  • Based on animal reproduction studies, there may be potential risks to the fetus from exposure to semaglutide during pregnancy.
  • Rybelsus or Ozempic tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Label revised Jan 30, 2026. DailyMed

Zepbound

  • To learn more please call or visit https://pregnancyregistry.lilly.com/zepbound.
  • Weight loss offers no benefit to a pregnant patient and may cause fetal harm.
  • Advise pregnant patients that weight loss is not recommended during pregnancy and to discontinue Zepbound when a pregnancy is recognized.
  • Reduced fetal weights associated with decreased maternal food consumption and body weights were observed at 0.1 mg/kg.

Label revised Aug 28, 2026. DailyMed

Mounjaro

  • Available data with Mounjaro use in pregnant women are insufficient to evaluate for a drug-related risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes.
  • There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy.
  • Based on animal reproduction studies, there may be risks to the fetus from exposure to tirzepatide during pregnancy.
  • Reduced fetal weights associated with decreased maternal food consumption and body weights were observed at 0.1 mg/kg.

Label revised Aug 27, 2026. DailyMed

Foundayo

  • Weight loss offers no benefit to a pregnant patient and may cause fetal harm.
  • When a pregnancy is recognized, advise the pregnant patient of the risk to a fetus and discontinue Foundayo.
  • There are no adequate and well-controlled studies of Foundayo during pregnancy.
  • Based on animal reproduction studies, there may be risks to the fetus from exposure to orforglipron during pregnancy.

Label revised Jul 29, 2026. DailyMed

Trulicity

  • Limited data with Trulicity in pregnant women are not sufficient to determine a drug-associated risk for major birth defects and miscarriage.
  • There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.
  • Based on animal reproduction studies, there may be risks to the fetus from exposure to dulaglutide during pregnancy.
  • Reduced fetal weights associated with decreased maternal food intake and decreased weight gain attributed to the pharmacology of dulaglutide were observed at ≥1.63 mg/kg.

Label revised Jun 16, 2026. DailyMed

Saxenda

  • Based on animal reproduction studies, there may be risks to the fetus from exposure to Saxenda during pregnancy.
  • Saxenda should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • Additionally, weight loss offers no benefit to a pregnant patient and may cause fetal harm.
  • When a pregnancy is recognized, advise the pregnant patient of the risk to a fetus, and discontinue Saxenda.

Label revised Feb 25, 2026. DailyMed

Victoza

  • Based on animal reproduction studies, there may be risks to the fetus from exposure to Victoza during pregnancy.
  • Victoza should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • Animal reproduction studies identified increased adverse developmental outcomes from exposure during pregnancy.
  • Poorly controlled diabetes in pregnancy increases the maternal risk for diabetic ketoacidosis, pre-eclampsia, spontaneous abortions, preterm delivery, and delivery complications.

Label revised Oct 14, 2025. DailyMed

Byetta

  • Limited data with Byetta in pregnant women are not sufficient to determine a drug-associated risk for major birth defects or miscarriage.
  • There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy.
  • Based on animal reproduction studies, there may be risks to the fetus from exposure to Byetta during pregnancy.
  • Byetta should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Label revised Sep 2, 2025. DailyMed

Not from trials

Reports to FDA about pregnancy

Counts of voluntary reports from patients and doctors. They cannot show that a medicine caused anything and cannot give a rate, and a brand used by more people draws more reports.

MedicineReports namingAll reports on it
MounjaroMiscarriage: 137 · Exposure during pregnancy: 2397,440
OzempicMiscarriage: 8370,863
WegovyMiscarriage: 71 · Pregnancy: 19 · Exposure during pregnancy: 1125,993
ZepboundMiscarriage: 63 · Exposure during pregnancy: 780,835
VictozaExposure during pregnancy: 46 · Miscarriage: 43 · Pregnancy: 2441,462
SaxendaMiscarriage: 30 · Exposure during pregnancy: 15 · Pregnancy: 97,270
ByettaMiscarriage: 2252,087
Rybelsus and Ozempic tabletsMiscarriage: 37,758

Counted through openFDA from FDA's Adverse Event Reporting System, refreshed weekly. One report can name several terms.

Updated automatically

Latest FDA label updates

Written from each source's own record as it changes. Every change on GLPcompare

Questions

Pregnancy on a GLP-1: common questions

Can you take Wegovy while pregnant?

Its FDA label: Weight loss offers no benefit to a pregnant patient and may cause fetal harm. When a pregnancy is recognized, advise the pregnant patient of the risk to a fetus.

Can you take Ozempic while pregnant?

Its FDA label: There are limited data with semaglutide use in pregnant women to inform a drug-associated risk for adverse developmental outcomes. There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.

Can you take Rybelsus while pregnant?

Its FDA label: Available data with semaglutide use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal outcomes. There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.

Can you take Zepbound while pregnant?

Its FDA label: To learn more please call or visit https://pregnancyregistry.lilly.com/zepbound. Weight loss offers no benefit to a pregnant patient and may cause fetal harm.

Can you take Mounjaro while pregnant?

Its FDA label: Available data with Mounjaro use in pregnant women are insufficient to evaluate for a drug-related risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes. There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy.

Can you take Foundayo while pregnant?

Its FDA label: Weight loss offers no benefit to a pregnant patient and may cause fetal harm. When a pregnancy is recognized, advise the pregnant patient of the risk to a fetus and discontinue Foundayo.

Can you take Trulicity while pregnant?

Its FDA label: Limited data with Trulicity in pregnant women are not sufficient to determine a drug-associated risk for major birth defects and miscarriage. There are clinical considerations regarding the risks of poorly controlled diabetes in pregnancy.

Can you take Saxenda while pregnant?

Its FDA label: Based on animal reproduction studies, there may be risks to the fetus from exposure to Saxenda during pregnancy. Saxenda should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Can you take Victoza while pregnant?

Its FDA label: Based on animal reproduction studies, there may be risks to the fetus from exposure to Victoza during pregnancy. Victoza should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Other side effects

Trial rates describe groups, not what one person will feel. Talk to your clinician before starting, stopping or changing a medicine.

GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.