From each FDA label
Do GLP-1s cause anxiety?
No current GLP-1 label prints a rate for anxiety in its main trial table.
Not from trials
Reports to FDA about anxiety
Counts of voluntary reports from patients and doctors. They cannot show that a medicine caused anything and cannot give a rate, and a brand used by more people draws more reports.
| Medicine | Reports naming | All reports on it |
|---|---|---|
| Ozempic | Anxiety: 1,240 · Nervousness: 294 · Panic attack: 146 | 70,863 |
| Mounjaro | Anxiety: 1,049 · Panic attack: 256 · Nervousness: 83 | 97,440 |
| Trulicity | Anxiety: 695 · Nervousness: 212 · Panic attack: 64 | 87,279 |
| Zepbound | Anxiety: 604 · Panic attack: 145 · Nervousness: 65 | 80,835 |
| Byetta | Nervousness: 530 · Anxiety: 457 · Panic attack: 45 | 52,087 |
| Wegovy | Anxiety: 503 · Panic attack: 101 · Nervousness: 72 | 25,993 |
| Victoza | Anxiety: 377 · Nervousness: 126 · Panic attack: 33 | 41,462 |
| Saxenda | Anxiety: 114 · Nervousness: 14 · Panic attack: 13 | 7,270 |
| Rybelsus and Ozempic tablets | Anxiety: 106 · Nervousness: 20 · Panic attack: 9 | 7,758 |
| Foundayo | Anxiety: 14 · Nervousness: 5 · Panic attack: 3 | 3,050 |
Counted through openFDA from FDA's Adverse Event Reporting System, refreshed weekly. One report can name several terms.
Updated automatically
Latest FDA label updates
- FDA labelFDA label updated: Zepbound (Eli Lilly and Company), effective 2026-08-28
- FDA labelFDA label updated: Mounjaro (Eli Lilly and Company), effective 2026-08-27
- FDA labelFDA label updated: Foundayo (Eli Lilly and Company), effective 2026-07-29
- FDA labelFDA label updated: Liraglutide (Meitheal Pharmaceuticals Inc.), effective 2026-07-27
- FDA labelFDA label updated: Liraglutide (NorthStar Rx LLC), effective 2026-06-24
Written from each source's own record as it changes. Every change on GLPcompare
Other side effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Indigestion
- Acid reflux
- Burping
- Gas
- Bloating
- Fatigue
- Headache
- Dizziness
- Hair loss
- Injection site reactions
- Skin sensitivity and tingling
- Taste changes
- Muscle loss
- Joint pain
- Insomnia
- Kidney stones
- Rash and itching
- Low blood pressure
- Bone loss
- UTIs and yeast infections
- Jaw pain and clenching
- Body aches
- Pancreatitis
- Gallbladder problems
- Low blood sugar
- Kidney problems
- Gastroparesis and severe stomach problems
- Allergic reactions
- Thyroid cancer
- Eye problems
- Fast heart rate
- Aspiration under anesthesia
- Depression and suicidal thoughts
- Birth control
- Drug interactions
- Taking two GLP-1s
- Metformin
- Pregnancy
- Breastfeeding
Trial rates describe groups, not what one person will feel. Talk to your clinician before starting, stopping or changing a medicine.
GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.