From each FDA label
Do GLP-1s cause body aches?
No current GLP-1 label prints a rate for body aches in its main trial table.
Not from trials
Reports to FDA about body aches
Counts of voluntary reports from patients and doctors. They cannot show that a medicine caused anything and cannot give a rate, and a brand used by more people draws more reports.
| Medicine | Reports naming | All reports on it |
|---|---|---|
| Ozempic | Back pain: 907 · Pain in extremity: 775 · Muscle spasms: 770 · Myalgia: 469 | 70,863 |
| Trulicity | Pain in extremity: 667 · Back pain: 633 · Muscle spasms: 476 · Myalgia: 264 | 87,279 |
| Mounjaro | Back pain: 600 · Myalgia: 591 · Pain in extremity: 510 · Muscle spasms: 483 | 97,440 |
| Byetta | Back pain: 560 · Pain in extremity: 535 · Muscle spasms: 401 · Myalgia: 259 | 52,087 |
| Victoza | Back pain: 552 · Pain in extremity: 419 · Muscle spasms: 365 · Myalgia: 244 | 41,462 |
| Zepbound | Muscle spasms: 338 · Back pain: 324 · Myalgia: 268 · Pain in extremity: 260 | 80,835 |
| Wegovy | Back pain: 282 · Muscle spasms: 232 · Pain in extremity: 201 · Myalgia: 165 | 25,993 |
| Rybelsus and Ozempic tablets | Pain in extremity: 100 · Back pain: 98 · Myalgia: 55 · Muscle spasms: 50 | 7,758 |
| Saxenda | Back pain: 86 · Muscle spasms: 71 · Pain in extremity: 41 · Myalgia: 28 | 7,270 |
| Foundayo | Muscle spasms: 18 · Myalgia: 10 · Pain in extremity: 10 · Back pain: 9 | 3,050 |
Counted through openFDA from FDA's Adverse Event Reporting System, refreshed weekly. One report can name several terms.
Updated automatically
Latest FDA label updates
- FDA labelFDA label updated: Zepbound (Eli Lilly and Company), effective 2026-08-28
- FDA labelFDA label updated: Mounjaro (Eli Lilly and Company), effective 2026-08-27
- FDA labelFDA label updated: Foundayo (Eli Lilly and Company), effective 2026-07-29
- FDA labelFDA label updated: Liraglutide (Meitheal Pharmaceuticals Inc.), effective 2026-07-27
- FDA labelFDA label updated: Liraglutide (NorthStar Rx LLC), effective 2026-06-24
Written from each source's own record as it changes. Every change on GLPcompare
Other side effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Indigestion
- Acid reflux
- Burping
- Gas
- Bloating
- Fatigue
- Headache
- Dizziness
- Hair loss
- Injection site reactions
- Skin sensitivity and tingling
- Taste changes
- Muscle loss
- Joint pain
- Insomnia
- Kidney stones
- Rash and itching
- Low blood pressure
- Anxiety
- Bone loss
- UTIs and yeast infections
- Jaw pain and clenching
- Pancreatitis
- Gallbladder problems
- Low blood sugar
- Kidney problems
- Gastroparesis and severe stomach problems
- Allergic reactions
- Thyroid cancer
- Eye problems
- Fast heart rate
- Aspiration under anesthesia
- Depression and suicidal thoughts
- Birth control
- Drug interactions
- Taking two GLP-1s
- Metformin
- Pregnancy
- Breastfeeding
Trial rates describe groups, not what one person will feel. Talk to your clinician before starting, stopping or changing a medicine.
GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.