From each FDA label
Do GLP-1s cause kidney stones?
We found no sentence on kidney stones in the parts of the current GLP-1 labels we read. A study of US veterans with diabetes linked GLP-1s to more kidney stones than usual care, which shows a link and not a cause.
Not from trials
Reports to FDA about kidney stones
Counts of voluntary reports from patients and doctors. They cannot show that a medicine caused anything and cannot give a rate, and a brand used by more people draws more reports.
| Medicine | Reports naming | All reports on it |
|---|---|---|
| Ozempic | Nephrolithiasis: 322 | 70,863 |
| Mounjaro | Nephrolithiasis: 230 | 97,440 |
| Trulicity | Nephrolithiasis: 219 | 87,279 |
| Byetta | Nephrolithiasis: 193 · Renal colic: 17 | 52,087 |
| Victoza | Nephrolithiasis: 142 | 41,462 |
| Zepbound | Nephrolithiasis: 119 | 80,835 |
| Wegovy | Nephrolithiasis: 80 | 25,993 |
| Saxenda | Nephrolithiasis: 36 · Renal colic: 4 | 7,270 |
| Rybelsus and Ozempic tablets | Nephrolithiasis: 32 · Renal colic: 4 | 7,758 |
Counted through openFDA from FDA's Adverse Event Reporting System, refreshed weekly. One report can name several terms.
Updated automatically
Latest FDA label updates
- FDA labelFDA label updated: Zepbound (Eli Lilly and Company), effective 2026-08-28
- FDA labelFDA label updated: Mounjaro (Eli Lilly and Company), effective 2026-08-27
- FDA labelFDA label updated: Foundayo (Eli Lilly and Company), effective 2026-07-29
- FDA labelFDA label updated: Liraglutide (Meitheal Pharmaceuticals Inc.), effective 2026-07-27
- FDA labelFDA label updated: Liraglutide (NorthStar Rx LLC), effective 2026-06-24
Written from each source's own record as it changes. Every change on GLPcompare
Other side effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Indigestion
- Acid reflux
- Burping
- Gas
- Bloating
- Fatigue
- Headache
- Dizziness
- Hair loss
- Injection site reactions
- Skin sensitivity and tingling
- Taste changes
- Muscle loss
- Joint pain
- Insomnia
- Rash and itching
- Low blood pressure
- Anxiety
- Bone loss
- UTIs and yeast infections
- Jaw pain and clenching
- Body aches
- Pancreatitis
- Gallbladder problems
- Low blood sugar
- Kidney problems
- Gastroparesis and severe stomach problems
- Allergic reactions
- Thyroid cancer
- Eye problems
- Fast heart rate
- Aspiration under anesthesia
- Depression and suicidal thoughts
- Birth control
- Drug interactions
- Taking two GLP-1s
- Metformin
- Pregnancy
- Breastfeeding
Trial rates describe groups, not what one person will feel. Talk to your clinician before starting, stopping or changing a medicine.
GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.