From each FDA label
Do GLP-1s cause insomnia?
We found no sentence on insomnia in the parts of the current GLP-1 labels we read. Saxenda's label does list insomnia, in its table of adverse reactions, rather than in a sentence.
Not from trials
Reports to FDA about insomnia
Counts of voluntary reports from patients and doctors. They cannot show that a medicine caused anything and cannot give a rate, and a brand used by more people draws more reports.
| Medicine | Reports naming | All reports on it |
|---|---|---|
| Ozempic | Insomnia: 810 | 70,863 |
| Mounjaro | Insomnia: 627 | 97,440 |
| Zepbound | Insomnia: 575 | 80,835 |
| Byetta | Insomnia: 488 | 52,087 |
| Trulicity | Insomnia: 459 | 87,279 |
| Victoza | Insomnia: 420 | 41,462 |
| Wegovy | Insomnia: 273 | 25,993 |
| Rybelsus and Ozempic tablets | Insomnia: 90 | 7,758 |
| Saxenda | Insomnia: 73 | 7,270 |
| Foundayo | Insomnia: 24 | 3,050 |
Counted through openFDA from FDA's Adverse Event Reporting System, refreshed weekly. One report can name several terms.
Updated automatically
Latest FDA label updates
- FDA labelFDA label updated: Zepbound (Eli Lilly and Company), effective 2026-08-28
- FDA labelFDA label updated: Mounjaro (Eli Lilly and Company), effective 2026-08-27
- FDA labelFDA label updated: Foundayo (Eli Lilly and Company), effective 2026-07-29
- FDA labelFDA label updated: Liraglutide (Meitheal Pharmaceuticals Inc.), effective 2026-07-27
- FDA labelFDA label updated: Liraglutide (NorthStar Rx LLC), effective 2026-06-24
Written from each source's own record as it changes. Every change on GLPcompare
Other side effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Indigestion
- Acid reflux
- Burping
- Gas
- Bloating
- Fatigue
- Headache
- Dizziness
- Hair loss
- Injection site reactions
- Skin sensitivity and tingling
- Taste changes
- Muscle loss
- Joint pain
- Kidney stones
- Rash and itching
- Low blood pressure
- Anxiety
- Bone loss
- UTIs and yeast infections
- Jaw pain and clenching
- Body aches
- Pancreatitis
- Gallbladder problems
- Low blood sugar
- Kidney problems
- Gastroparesis and severe stomach problems
- Allergic reactions
- Thyroid cancer
- Eye problems
- Fast heart rate
- Aspiration under anesthesia
- Depression and suicidal thoughts
- Birth control
- Drug interactions
- Taking two GLP-1s
- Metformin
- Pregnancy
- Breastfeeding
Trial rates describe groups, not what one person will feel. Talk to your clinician before starting, stopping or changing a medicine.
GLPcompare is an informational data platform, not a medical provider or pharmacy. Nothing here is medical advice, a diagnosis, or a recommendation to start, stop, or change any treatment. Data is aggregated from public sources and can be incomplete or out of date. Always confirm with a licensed clinician and the current FDA label.